Area of research
Nephrology · Surgery
Research interest
Research interests include Renal Diseases and Glomerulopathies, Organ Transplantation Techniques and Outcomes, Liver physiology and pathology, and Immune cells in cancer.
Tumor-produced ammonia is metabolized by regulatory T cells to further impede anti-tumor immunity
Macrophage Nogo-B Drives Liver Fibrosis
Integrated single-cell and spatial transcriptomic profiling reveals that CD177<sup>+</sup> Tregs enhance immunosuppression through apoptosis and resistance to immunotherapy in hepatocellular carcinoma.
FAD synthase confers ferroptosis resistance and restrains CD8<sup>+</sup> T cell recruitment in hepatocellular carcinoma.
Correction: Tumor-resident microbiota contributes to colorectal cancer liver metastasis by lactylation and immune modulation.
PSME3 drives Tregs infiltration and anti-PD1 resistance in hepatocellular carcinoma by regulating FBXL7/PTEN-mediated metabolic reprogramming.
Tumor-resident microbiota contributes to colorectal cancer liver metastasis by lactylation and immune modulation.
POSTN<sup>+</sup> cancer-associated fibroblasts determine the efficacy of immunotherapy in hepatocellular carcinoma.
Genetic Engineering in Bacteria, Fungi, and Oomycetes, Taking Advantage of CRISPR
Integrated single-cell transcriptomics reveals the hypoxia-induced inflammation-cancer transformation in NASH-derived hepatocellular carcinoma.
Macrophage ATG16L1 expression suppresses metabolic dysfunction-associated steatohepatitis progression by promoting lipophagy
E2F2 Reprograms Macrophage Function By Modulating Material and Energy Metabolism in the Progression of Metabolic Dysfunction-Associated Steatohepatitis.
ATG16L1 Depletion-Mediated Activation of the TRAF1 Signaling in Macrophages Aggravates Liver Fibrosis.
Biomimetic Enzyme Cascade Structural Color Hydrogel Microparticles for Diabetic Wound Healing Management
Piezoelectric biomaterials for neural tissue engineering
Ultrasound‐Responsive Composited Conductive Silk Conduits for Peripheral Nerve Regeneration
Natural Multifunctional Silk Microcarriers for Noise‐Induced Hearing Loss Therapy
Peroxisome Deficiency in Cochlear Hair Cells Causes Hearing Loss by Deregulating BK Channels
Spontaneous development of an autoimmune hepatitis - primary biliary cholangitis overlap syndrome in dnTGFβRII Aire<sup>-/-</sup> mice.
Tumor metabolite lactate promotes tumorigenesis by modulating MOESIN lactylation and enhancing TGF-β signaling in regulatory T cells
Tumor metabolite lactate promotes tumorigenesis by modulating MOESIN lactylation and enhancing TGF-β signaling in regulatory T cells
XBP1 deficiency promotes hepatocyte pyroptosis by impairing mitophagy to activate mtDNA-cGAS-STING signaling in macrophages during acute liver injury
XBP1 deficiency promotes hepatocyte pyroptosis by impairing mitophagy to activate mtDNA-cGAS-STING signaling in macrophages during acute liver injury
FSTL1 promotes liver fibrosis by reprogramming macrophage function through modulating the intracellular function of PKM2.
Gut microbiota as prognosis markers for patients with HBV-related acute-on-chronic liver failure
Myeloid Nrf2 deficiency aggravates non-alcoholic steatohepatitis progression by regulating YAP-mediated NLRP3 inflammasome signaling
The proportion of CD19+CD24hiCD27+ regulatory B cells predicts the occurrence of acute allograft rejection in liver transplantation
Loss of ATF3 exacerbates liver damage through the activation of mTOR/p70S6K/ HIF-1α signaling pathway in liver inflammatory injury
ATF3-Mediated NRF2/HO-1 Signaling Regulates TLR4 Innate Immune Responses in Mouse Liver Ischemia/Reperfusion Injury
Myeloid PTEN Deficiency Protects Livers from Ischemia Reperfusion Injury by Facilitating M2 Macrophage Differentiation