Area of research
Molecular Biology · Genetics
Research interest
Research interests include Genomics and Chromatin Dynamics, Genomics and Phylogenetic Studies, RNA Research and Splicing, and RNA and protein synthesis mechanisms.
Functional dissection of complex trait variants at single-nucleotide resolution
Machine-guided design of cell-type-targeting cis-regulatory elements
Deciphering the impact of genomic variation on function
Multicenter integrated analysis of noncoding CRISPRi screens
Vocal learning–associated convergent evolution in mammalian proteins and regulatory elements
Functional dissection of complex and molecular trait variants at single nucleotide resolution
Somatic mosaicism in schizophrenia brains reveals prenatal mutational processes
Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever
Evolutionary constraint and innovation across hundreds of placental mammals
Integrating gene annotation with orthology inference at scale
Leveraging base-pair mammalian constraint to understand genetic variation and human disease
Three-dimensional genome rewiring in loci with human accelerated regions
The contribution of historical processes to contemporary extinction risk in placental mammals
The functional and evolutionary impacts of human-specific deletions in conserved elements
Evolutionary constraint and innovation across hundreds of placental mammals
Leveraging Base Pair Mammalian Constraint to Understand Genetic Variation and Human Disease
Comparative genomics of Balto, a famous historic dog, captures lost diversity of 1920s sled dogs
Evolution of the ancestral mammalian karyotype and syntenic regions
Genome-wide functional screen of 3′UTR variants uncovers causal variants for human disease and evolution
Direct characterization of cis-regulatory elements and functional dissection of complex genetic associations using HCR–FlowFISH
Detection of Neanderthal Adaptively Introgressed Genetic Variants That Modulate Reporter Gene Expression in Human Immune Cells
Transmission from vaccinated individuals in a large SARS-CoV-2 Delta variant outbreak
Synthetic DNA spike-ins (SDSIs) enable sample tracking and detection of inter-sample contamination in SARS-CoV-2 sequencing workflows
Author Correction: Direct characterization of cis-regulatory elements and functional dissection of complex genetic associations using HCR–FlowFISH
Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events
Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features
Direct Identification of Hundreds of Expression-Modulating Variants using a Multiplexed Reporter Assay
The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment
Coexpression Networks Implicate Human Midfetal Deep Cortical Projection Neurons in the Pathogenesis of Autism