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Jürgen Kopitz

Heidelberg University · DE
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Area of research
Molecular Biology · Immunology
Research interest
Research interests include Glycosylation and Glycoproteins Research, Galectins and Cancer Biology, Metabolism and Genetic Disorders, and Retinal Diseases and Treatments.
h-index
51
citations
8,447
works
1,318
NIH funding
primary concept
email

Recent publications

Combining Recombinase-Mediated Cassette Exchange Strategy with Quantitative Proteomic and Phosphoproteomic Analyses to Inspect Intracellular Functions of the Tumor Suppressor Galectin-4 in Colorectal Cancer Cells
International Journal of Molecular Sciences 2022cited by 10position: lastdoi
Proinflammatory Extracellular Vesicle-Mediated Signaling Contributes to the Induction of Neuroinflammation in Animal Models of Endotoxemia and Peripheral Surgical Stress.
2021cited by 18position: contributordoi
Treatment resistance analysis reveals GLUT‐1‐mediated glucose uptake as a major target of synthetic rocaglates in cancer cells
Cancer Medicine 2021cited by 5position: middledoi
Differential Glycosite Profiling—A Versatile Method to Compare Membrane Glycoproteomes
Molecules 2021cited by 2position: lastdoi
Correction to: Proinflammatory Extracellular Vesicle-Mediated Signaling Contributes to the Induction of Neuroinflammation in Animal Models of Endotoxemia and Peripheral Surgical Stress.
2021cited by 0position: contributordoi
(Phospho)proteomic Profiling of Microsatellite Unstable CRC Cells Reveals Alterations in Nuclear Signaling and Cholesterol Metabolism Caused by Frameshift Mutation of NMD Regulator UPF3A
International Journal of Molecular Sciences 2020cited by 9position: middledoi
SILAC-Based Quantification of TGFBR2-Regulated Protein Expression in Extracellular Vesicles of Microsatellite Unstable Colorectal Cancers
International Journal of Molecular Sciences 2019cited by 25position: middledoi
Chicken lens development: complete signature of expression of galectins during embryogenesis and evidence for their complex formation with α-, β-, δ-, and τ-crystallins, N-CAM, and N-cadherin obtained by affinity chromatography
Cell and Tissue Research 2019cited by 18position: middledoi
Deciphering the galectin-12 protein interactome reveals a major impact of galectin-12 on glutamine anaplerosis in colon cancer cells
Experimental Cell Research 2019cited by 7position: lastdoi
Detection of malignancy‐associated phosphoproteome changes in human colorectal cancer induced by cell surface binding of growth‐inhibitory galectin‐4
IUBMB Life 2018cited by 14position: lastdoi
Chicken GRIFIN: binding partners, developmental course of localization and activation of its lens-specific gene expression by L-Maf/Pax6
Cell and Tissue Research 2018cited by 13position: middledoi
Galectin-12 colocalizes with splicing factor-rich speckles and shuttles between the nucleus and cytoplasm in colon cancer cells
2018cited by 3position: last
TGFBR2-dependent alterations of exosomal cargo and functions in DNA mismatch repair-deficient HCT116 colorectal cancer cells
Cell Communication and Signaling 2017cited by 36position: middledoi
Lipid glycosylation: a primer for histochemists and cell biologists
Histochemistry and Cell Biology 2016cited by 95position: firstdoi
Intra- and intermolecular interactions of human galectin-3: assessment by full-assignment-based NMR
Glycobiology 2016cited by 83position: middledoi
The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration
Nature Communications 2016cited by 68position: middledoi
Chicken GRIFIN: A homodimeric member of the galectin network with canonical properties and a unique expression profile
Biochimie 2016cited by 29position: middledoi
HMGB1: The metabolic weapon in the arsenal of NK cells
Molecular & Cellular Oncology 2016cited by 19position: middledoi
Reconstitution of TGFBR2 in HCT116 colorectal cancer cells causes increased LFNG expression and enhanced N-acetyl-d-glucosamine incorporation into Notch1
Cellular Signalling 2016cited by 19position: middledoi
Combining Click Chemistry-Based Proteomics With Dox-Inducible Gene Expression
Methods in enzymology on CD-ROM/Methods in enzymology 2016cited by 1position: lastdoi
A new method for detection of tumor driver‐dependent changes of protein sialylation in a colon cancer cell line reveals nectin‐3 as TGFBR2 target
Protein Science 2015cited by 42position: lastdoi
The ribosomal protein S6 in renal cell carcinoma: functional relevance and potential as biomarker
Oncotarget 2015cited by 40position: middledoi
Structural significance of galectin design: impairment of homodimer stability by linker insertion and partial reversion by ligand presence
Protein Engineering Design and Selection 2015cited by 35position: middledoi
Reconstitution of TGFBR2-Mediated Signaling Causes Upregulation of GDF-15 in HCT116 Colorectal Cancer Cells
PLoS ONE 2015cited by 11position: middledoi
Human chimera-type galectin-3: Defining the critical tail length for high-affinity glycoprotein/cell surface binding and functional competition with galectin-1 in neuroblastoma cell growth regulation
Biochimie 2014cited by 49position: firstdoi
De Novo Proteome Analysis of Genetically Modified Tumor Cells By a Metabolic Labeling/Azide-alkyne Cycloaddition Approach
Molecular & Cellular Proteomics 2014cited by 8position: lastdoi
A multiplex method for the detection of serum antibodies against in silico-predicted tumor antigens
Cancer Immunology Immunotherapy 2014cited by 8position: middledoi
In-depth mass spectrometric mapping of the human vitreous proteome
Proteome Science 2013cited by 70position: lastdoi
T cell responses against microsatellite instability-induced frameshift peptides and influence of regulatory T cells in colorectal cancer
Cancer Immunology Immunotherapy 2012cited by 55position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Martina Schnölzer · Heidelberg University14 papers (2013–2019)Uwe Warnken · German Cancer Research Center11 papers (2013–2021)Johannes Gebert · Medical University of Vienna11 papers (2014–2022)Malwina Michalak · German Cancer Research Center9 papers (2015–2022)Hans‐Joachim Gabius · Ludwig-Maximilians-Universität München7 papers (2014–2019)Matthias Kloor · European Molecular Biology Organization5 papers (2012–2021)Magnus von Knebel Doeberitz · Hospital Sírio-Libanês4 papers (2012–2021)Herbert Kaltner · Ludwig-Maximilians-Universität München4 papers (2016–2022)Sabine André · Ludwig-Maximilians-Universität München4 papers (2014–2016)Gabriel García Caballero · Ludwig-Maximilians-Universität München3 papers (2016–2019)Fabia Fricke · German Cancer Research Center3 papers (2015–2019)Peter Schirmacher · Kliniken Essen-Mitte3 papers (2015–2016)Jennifer Lee · The Catholic University of Korea Seoul St. Mary's Hospital3 papers (2014–2017)Eva‐Maria Katzenmaier · National Center for Tumor Diseases3 papers (2016–2020)Anna‐Kristin Ludwig · Ludwig-Maximilians-Universität München3 papers (2016–2019)Wilfried Roth · Johannes Gutenberg University Mainz3 papers (2015–2016)Sabine Vértesy · Ludwig-Maximilians-Universität München3 papers (2014–2016)Joachim C. Manning · Ludwig-Maximilians-Universität München3 papers (2016–2019)Sebastian Schmidt · Ludwig-Maximilians-Universität München3 papers (2016–2019)Georg Gdynia · German Cancer Research Center2 papers (2016–2016)
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