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Ángel Cedazo-Mı́nguez

Karolinska Institutet · SE
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Area of research
Physiology · Surgery
Research interest
Research interests include Alzheimer's disease research and treatments, Cholesterol and Lipid Metabolism, Cholinesterase and Neurodegenerative Diseases, and Receptor Mechanisms and Signaling.
h-index
47
citations
8,655
works
149
NIH funding
primary concept
email

Recent publications

CYP46A1-mediated cholesterol turnover induces sex-specific changes in cognition and counteracts memory loss in ovariectomized mice
Science Advances 2024cited by 26position: middledoi
A cell autonomous regulator of neuronal excitability modulates tau in Alzheimer’s disease vulnerable neurons
Brain 2024cited by 16position: middledoi
Alzheimer’s disease biomarker profiling in a memory clinic cohort without common comorbidities
Brain Communications 2023cited by 11position: middledoi
Alzheimer’s disease biomarker profiling in a memory clinic cohort without common comorbidities
Alzheimer s & Dementia 2023cited by 0position: middledoi
Alzheimer’s disease biomarker profiling in a memory clinic cohort without common comorbidities
bioRxiv (Cold Spring Harbor Laboratory) 2022cited by 3position: middledoi
Sex-dependent effects of CYP46A1 overexpression on cognitive function during aging
bioRxiv (Cold Spring Harbor Laboratory) 2021cited by 5position: middledoi
Current and emerging avenues for Alzheimer's disease drug targets
Journal of Internal Medicine 2019cited by 139position: middledoi
Cross-disease analysis of Alzheimer’s disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases
Scientific Reports 2019cited by 91position: middledoi
24(S),25-Epoxycholesterol and cholesterol 24S-hydroxylase (CYP46A1) overexpression promote midbrain dopaminergic neurogenesis in vivo
Journal of Biological Chemistry 2019cited by 47position: middledoi
Evidence for sex difference in the <scp>CSF</scp>/plasma albumin ratio in ~20 000 patients and 335 healthy volunteers
Journal of Cellular and Molecular Medicine 2018cited by 90position: middledoi
The composition of polypharmacy: A register-based study of Swedes aged 75 years and older
PLoS ONE 2018cited by 86position: middledoi
27-Hydroxycholesterol Induces Aberrant Morphology and Synaptic Dysfunction in Hippocampal Neurons
Cerebral Cortex 2018cited by 69position: lastdoi
Tau hyperphosphorylation induces oligomeric insulin accumulation and insulin resistance in neurons
Brain 2017cited by 95position: lastdoi
Can <scp>LDL</scp> cholesterol be too low? Possible risks of extremely low levels
Journal of Internal Medicine 2017cited by 94position: middledoi
27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation
The Journal of Experimental Medicine 2017cited by 82position: lastdoi
Defeating Alzheimer's disease and other dementias: a priority for European science and society
The Lancet Neurology 2016cited by 1,679position: middledoi
Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia
Alzheimer s & Dementia 2016cited by 171position: middledoi
Anthocyanins protect from complex I inhibition and APPswe mutation through modulation of the mitochondrial fission/fusion pathways
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2016cited by 38position: lastdoi
Oxidative Stress in Alzheimer’s Disease: Why Did Antioxidant Therapy Fail?
Oxidative Medicine and Cellular Longevity 2014cited by 303position: lastdoi
Pathways to Alzheimer's disease
Journal of Internal Medicine 2014cited by 185position: middledoi
Decreased levels of guanosine 3′, 5′‐monophosphate (c<scp>GMP</scp>) in cerebrospinal fluid (<scp>CSF</scp>) are associated with cognitive decline and amyloid pathology in <scp>A</scp>lzheimer's disease
Neuropathology and Applied Neurobiology 2014cited by 108position: middledoi
Vitamin D in Relation to Cognitive Impairment, Cerebrospinal Fluid Biomarkers, and Brain Volumes
The Journals of Gerontology Series A 2014cited by 80position: middledoi
Alterations in brain leptin signalling in spite of unchanged <scp>CSF</scp> leptin levels in Alzheimer's disease
Aging Cell 2014cited by 74position: middledoi
27-Hydroxycholesterol mediates negative effects of dietary cholesterol on cognition in mice
Behavioural Brain Research 2014cited by 61position: middledoi
A new metabolomic workflow for early detection of Alzheimer's disease
Journal of Chromatography A 2013cited by 98position: middledoi
Is It Possible to Improve Memory Function by Upregulation of the Cholesterol 24S-Hydroxylase (CYP46A1) in the Brain?
PLoS ONE 2013cited by 76position: middledoi
Toward a Predictive Model of Alzheimer’s Disease Progression Using Capillary Electrophoresis–Mass Spectrometry Metabolomics
Analytical Chemistry 2012cited by 174position: middledoi
Intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system
Translational Neurodegeneration 2012cited by 70position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Bengt Winblad · Karolinska University Hospital12 papers (2012–2024)Silvia Maioli · Karolinska Institutet12 papers (2013–2024)Patricia Rodriguez‐Rodriguez · Karolinska Institutet9 papers (2016–2024)Ingemar Björkhem · Karolinska Institutet8 papers (2013–2024)Miia Kivipelto · Karolinska University Hospital8 papers (2012–2024)Anna Matton · Public Health Agency of Sweden7 papers (2016–2024)Paula Merino‐Serrais · Instituto Cajal6 papers (2014–2024)Kaj Blennow · First Affiliated Hospital of Anhui Medical University6 papers (2018–2024)William J. Griffiths · Swansea University6 papers (2019–2024)Henrik Zetterberg · Indian Institute of Science Bangalore5 papers (2014–2024)Francesca Eroli · Karolinska Institutet5 papers (2021–2024)Yuqin Wang · Shandong University5 papers (2019–2024)Manuela Pacciarini · Swansea University5 papers (2021–2024)Cristina Parrado‐Fernández · AlzeCure Pharma (Sweden)4 papers (2016–2018) · 4 papers (2021–2024)Nenad Bogdanović · Karolinska Institutet4 papers (2014–2023) · 3 papers (2013–2017) · 3 papers (2022–2023)Julen Goikolea · University of Massachusetts Chan Medical School3 papers (2022–2023)Ann Brinkmalm · Sahlgrenska University Hospital3 papers (2022–2023)
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