Area of research
Physiology · Surgery
Research interest
Research interests include Alzheimer's disease research and treatments, Cholesterol and Lipid Metabolism, Cholinesterase and Neurodegenerative Diseases, and Receptor Mechanisms and Signaling.
CYP46A1-mediated cholesterol turnover induces sex-specific changes in cognition and counteracts memory loss in ovariectomized mice
A cell autonomous regulator of neuronal excitability modulates tau in Alzheimer’s disease vulnerable neurons
Alzheimer’s disease biomarker profiling in a memory clinic cohort without common comorbidities
Alzheimer’s disease biomarker profiling in a memory clinic cohort without common comorbidities
Alzheimer’s disease biomarker profiling in a memory clinic cohort without common comorbidities
Sex-dependent effects of CYP46A1 overexpression on cognitive function during aging
Current and emerging avenues for Alzheimer's disease drug targets
Cross-disease analysis of Alzheimer’s disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases
24(S),25-Epoxycholesterol and cholesterol 24S-hydroxylase (CYP46A1) overexpression promote midbrain dopaminergic neurogenesis in vivo
Evidence for sex difference in the <scp>CSF</scp>/plasma albumin ratio in ~20 000 patients and 335 healthy volunteers
The composition of polypharmacy: A register-based study of Swedes aged 75 years and older
27-Hydroxycholesterol Induces Aberrant Morphology and Synaptic Dysfunction in Hippocampal Neurons
Tau hyperphosphorylation induces oligomeric insulin accumulation and insulin resistance in neurons
Can <scp>LDL</scp> cholesterol be too low? Possible risks of extremely low levels
27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation
Defeating Alzheimer's disease and other dementias: a priority for European science and society
Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia
Anthocyanins protect from complex I inhibition and APPswe mutation through modulation of the mitochondrial fission/fusion pathways
Oxidative Stress in Alzheimer’s Disease: Why Did Antioxidant Therapy Fail?
Pathways to Alzheimer's disease
Decreased levels of guanosine 3′, 5′‐monophosphate (c<scp>GMP</scp>) in cerebrospinal fluid (<scp>CSF</scp>) are associated with cognitive decline and amyloid pathology in <scp>A</scp>lzheimer's disease
Vitamin D in Relation to Cognitive Impairment, Cerebrospinal Fluid Biomarkers, and Brain Volumes
Alterations in brain leptin signalling in spite of unchanged <scp>CSF</scp> leptin levels in Alzheimer's disease
27-Hydroxycholesterol mediates negative effects of dietary cholesterol on cognition in mice
A new metabolomic workflow for early detection of Alzheimer's disease
Is It Possible to Improve Memory Function by Upregulation of the Cholesterol 24S-Hydroxylase (CYP46A1) in the Brain?
Toward a Predictive Model of Alzheimer’s Disease Progression Using Capillary Electrophoresis–Mass Spectrometry Metabolomics
Intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system
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