Area of research
Molecular Biology · Plant Science
Research interest
Research interests include Genomics and Chromatin Dynamics, RNA Research and Splicing, Epigenetics and DNA Methylation, and RNA and protein synthesis mechanisms.
An integrated view of the structure and function of the human 4D nucleome
Extrachromosomal DNA micronucleation constrains tumour fitness and improves patient survival
Extensive folding variability between homologous chromosomes in mammalian cells
Cryosectioning-enhanced super-resolution microscopy for single-protein imaging across cells and tissues
Epigenetic regulatory layers in the 3D nucleus
SRRM2 splicing factor modulates cell fate in early development
Multiplex-GAM: genome-wide identification of chromatin contacts yields insights overlooked by Hi-C
A noncoding single-nucleotide polymorphism at 8q24 drives <i>IDH1</i> -mutant glioma formation
Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos
Cell-type specialization is encoded by specific chromatin topologies
Comparison of the Hi-C, GAM and SPRITE methods using polymer models of chromatin
The dynamics of chromatin architecture in brain development and function
Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine
GAMIBHEAR: whole-genome haplotype reconstruction from Genome Architecture Mapping data
LifeTime and improving European healthcare through cell-based interceptive medicine
Evolving methodologies and concepts in 4D nucleome research
Methods for mapping 3D chromosome architecture
R-Loops Enhance Polycomb Repression at a Subset of Developmental Regulator Genes
Challenges and guidelines toward 4D nucleome data and model standards
Complex multi-enhancer contacts captured by genome architecture mapping
Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment
Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells
RNA polymerase II primes Polycomb‐repressed developmental genes throughout terminal neuronal differentiation