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Lauren L. Ritterhouse

Boston Foundation ·
Area of research
Cancer Research · Pulmonary and Respiratory Medicine
Research interest
Research interests include Cancer Genomics and Diagnostics, Lung Cancer Treatments and Mutations, Ovarian cancer diagnosis and treatment, and Genetic factors in colorectal cancer.
h-index
35
citations
6,569
works
160
NIH funding
primary concept
email

Recent publications

CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors
Nature 2024cited by 145position: middledoi
Rapid tumor DNA analysis of cerebrospinal fluid accelerates treatment of central nervous system lymphoma
Blood 2024cited by 26position: middledoi
Recommendations for Tumor Mutational Burden Assay Validation and Reporting
Journal of Molecular Diagnostics 2024cited by 21position: middledoi
Diagnostic quality model (DQM): an integrated framework for the assessment of diagnostic quality when using AI/ML
Clinical Chemistry and Laboratory Medicine (CCLM) 2023cited by 23position: lastdoi
Prognostic biomarkers for survival in mucosal melanoma
Pigment Cell & Melanoma Research 2023cited by 7position: middledoi
Abstract CT228: Concordance between tissue and circulating tumor DNA (ctDNA) testing for neurotrophic tyrosine receptor kinase (<i>NTRK</i>) gene fusions in larotrectinib (laro) clinical trials
Cancer Research 2023cited by 2position: middledoi
Diagnostic Value of MAML2 Rearrangements in Mucoepidermoid Carcinoma
International Journal of Molecular Sciences 2022cited by 20position: middledoi
Uterine PEComas: correlation between melanocytic marker expression and TSC alterations/TFE3 fusions
Modern Pathology 2021cited by 53position: middledoi
Embryonal rhabdomyosarcoma of the uterine corpus: a clinicopathological and molecular analysis of 21 cases highlighting a frequent association with DICER1 mutations
Modern Pathology 2021cited by 43position: middledoi
Development of a qualitative real-time RT-PCR assay for the detection of SARS-CoV-2: a guide and case study in setting up an emergency-use, laboratory-developed molecular microbiological assay
Journal of Clinical Pathology 2021cited by 15position: middledoi
<i>BAP1</i>-Mutated Clear Cell Renal Cell Carcinoma
American Journal of Clinical Pathology 2020cited by 53position: middledoi
Seven-Year Follow-Up Analysis of Adjuvant Paclitaxel and Trastuzumab Trial for Node-Negative, Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer
Journal of Clinical Oncology 2019cited by 277position: middledoi
Secondary resistance to immunotherapy associated with β-catenin pathway activation or PTEN loss in metastatic melanoma
Journal for ImmunoTherapy of Cancer 2019cited by 157position: middledoi
Genetic Underpinnings of Renal Cell Carcinoma With Leiomyomatous Stroma
The American Journal of Surgical Pathology 2019cited by 52position: middledoi
Loss of SMAD4 protein expression in gastrointestinal and extra‐gastrointestinal carcinomas
Histopathology 2019cited by 47position: firstdoi
Germline <i>BRCA</i> -Associated Endometrial Carcinoma Is a Distinct Clinicopathologic Entity
Clinical Cancer Research 2019cited by 46position: middledoi
Female adnexal tumors of probable Wolffian origin: morphological, immunohistochemical, and molecular analysis of 15 cases
Modern Pathology 2019cited by 42position: middledoi
High <i>NPM1</i> mutant allele burden at diagnosis correlates with minimal residual disease at first remission in de novo acute myeloid leukemia
American Journal of Hematology 2019cited by 31position: middledoi
Quantitative next-generation sequencing-based analysis indicates progressive accumulation of microsatellite instability between atypical hyperplasia/endometrial intraepithelial neoplasia and paired endometrioid endometrial carcinoma
Modern Pathology 2019cited by 29position: lastdoi
Integrating a Large Next-Generation Sequencing Panel into the Clinical Diagnosis of Gliomas Provides a Comprehensive Platform for Classification from FFPE Tissue or Smear Preparations
Journal of Neuropathology & Experimental Neurology 2019cited by 27position: middledoi
Fewer actionable mutations but higher tumor mutational burden characterizes NSCLC in black patients at an urban academic medical center
Oncotarget 2019cited by 24position: middledoi
Measurable residual disease monitoring for patients with acute myeloid leukemia following hematopoietic cell transplantation using error corrected hybrid capture next generation sequencing
PLoS ONE 2019cited by 24position: middledoi
Multi-Institutional Evaluation of Interrater Agreement of Variant Classification Based on the 2017 Association for Molecular Pathology, American Society of Clinical Oncology, and College of American Pathologists Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer
Journal of Molecular Diagnostics 2019cited by 20position: middledoi
Frequency of Germline Mutations in Cancer Susceptibility Genes in Malignant Mesothelioma
Journal of Clinical Oncology 2018cited by 226position: middledoi
Are Sporadic Eosinophilic Solid and Cystic Renal Cell Carcinomas Characterized by Somatic Tuberous Sclerosis Gene Mutations?
The American Journal of Surgical Pathology 2018cited by 75position: middledoi
Clinical Activity of Olaparib in Urothelial Bladder Cancer With DNA Damage Response Gene Mutations
JCO Precision Oncology 2018cited by 31position: middledoi
Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in <i>ALK</i> -Rearranged Lung Cancer
Cancer Discovery 2016cited by 1,140position: middledoi
Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer
Oncotarget 2016cited by 616position: middledoi
Association of Polymerase e–Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1
JAMA Oncology 2015cited by 675position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Jeremy P. Segal · University of Chicago11 papers (2018–2020)Sabah Kadri · Northwestern University8 papers (2018–2019)Sushant Patil · University of North Carolina at Chapel Hill4 papers (2018–2019)Pankhuri Wanjari · University of Chicago4 papers (2019–2021)Megan Parilla · NorthShore University HealthSystem4 papers (2018–2020)Tatjana Antic · University of Chicago3 papers (2018–2020)Jennifer A. Bennett · University of Chicago3 papers (2019–2021)Brooke E. Howitt · Cancer Institute (WIA)3 papers (2015–2019)Esther Oliva · Harvard University3 papers (2019–2021)Larissa V. Furtado · St. Jude Children's Research Hospital3 papers (2019–2024)Susan J. Hsiao · New York University2 papers (2019–2024)André Pinto · University of Miami2 papers (2021–2021)Panagiotis A. Konstantinopoulos · Harvard University2 papers (2015–2016)Kyle C. Strickland · Jackson Laboratory2 papers (2015–2016)Sachet A. Shukla · The University of Texas MD Anderson Cancer Center2 papers (2015–2016)Aliya N. Husain · University of Illinois Chicago2 papers (2018–2019)Lynette M. Sholl · Harvard University2 papers (2015–2019)Robert H. Young · University of Oklahoma Health Sciences Center2 papers (2019–2021)George F. Steinhardt · Helen DeVos Children's Hospital2 papers (2019–2019)Julia Thierauf · Foundation Medicine (United States)2 papers (2023–2023)