Area of research
Molecular Biology · Clinical Biochemistry
Research interest
Research interests include Chemistry, Amino acid, Biology, Deamidation, Crystallin, and Lens (geology).
Identification of Age- and Cataract-Related Changes in High-Density Lens Protein Aggregates
Changes in Phospholipid Composition of the Human Cerebellum and Motor Cortex during Normal Ageing
Tau Is Truncated in Five Regions of the Normal Adult Human Brain
Spontaneous Cleavage at Glu and Gln Residues in Long-Lived Proteins
New insights into the mechanisms of age-related protein-protein crosslinking in the human lens
Spontaneous protein–protein crosslinking at glutamine and glutamic acid residues in long-lived proteins
Molecular Processes Implicated in Human Age-Related Nuclear Cataract
Spatiotemporal changes in the human lens proteome: Critical insights into long-lived proteins
Mechanism of protein cleavage at asparagine leading to protein–protein cross-links
Cleavage C-terminal to Asp leads to covalent crosslinking of long-lived human proteins
Spontaneous cross-linking of proteins at aspartate and asparagine residues is mediated via a succinimide intermediate
DehydroalanylGly, a new post translational modification resulting from the breakdown of glutathione
Can the Fact That Myelin Proteins Are Old and Break down Explain the Origin of Multiple Sclerosis in Some People?
The phospholipid composition of the human entorhinal cortex remains relatively stable over 80 years of adult aging
Hotspots of age-related protein degradation: the importance of neighboring residues for the formation of non-disulfide crosslinks derived from cysteine
Old Proteins in Man: A Field in its Infancy
Amyloid Plaque in the Human Brain Can Decompose from Aβ(1-40/1-42) by Spontaneous Nonenzymatic Processes
Isoaspartic acid is present at specific sites in myelin basic protein from multiple sclerosis patients: could this represent a trigger for disease onset?
The etiology of human age-related cataract. Proteins don't last forever
Human prefrontal cortex phospholipids containing docosahexaenoic acid increase during normal adult aging, whereas those containing arachidonic acid decrease
Decreases in Phospholipids Containing Adrenic and Arachidonic Acids Occur in the Human Hippocampus over the Adult Lifespan
Old proteins and the <scp>A</scp>chilles heel of mass spectrometry. The role of proteomics in the etiology of human cataract
Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?
Molecular signatures of long‐lived proteins: autolytic cleavage adjacent to serine residues