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Michael G. Friedrich

University of Wollongong · AU
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Area of research
Molecular Biology · Clinical Biochemistry
Research interest
Research interests include Chemistry, Amino acid, Biology, Deamidation, Crystallin, and Lens (geology).
h-index
citations
825
works
24
NIH funding
primary concept
email

Recent publications

Identification of Age- and Cataract-Related Changes in High-Density Lens Protein Aggregates
Investigative Ophthalmology & Visual Science 2025cited by 9position: middledoi
Changes in Phospholipid Composition of the Human Cerebellum and Motor Cortex during Normal Ageing
Nutrients 2022cited by 23position: middledoi
Tau Is Truncated in Five Regions of the Normal Adult Human Brain
International Journal of Molecular Sciences 2021cited by 17position: firstdoi
Spontaneous Cleavage at Glu and Gln Residues in Long-Lived Proteins
ACS Chemical Biology 2021cited by 13position: firstdoi
New insights into the mechanisms of age-related protein-protein crosslinking in the human lens
Experimental Eye Research 2021cited by 13position: middledoi
Spontaneous protein–protein crosslinking at glutamine and glutamic acid residues in long-lived proteins
Biochemical Journal 2020cited by 10position: firstdoi
Molecular Processes Implicated in Human Age-Related Nuclear Cataract
Investigative Ophthalmology & Visual Science 2019cited by 69position: lastdoi
Spatiotemporal changes in the human lens proteome: Critical insights into long-lived proteins
Progress in Retinal and Eye Research 2019cited by 51position: middledoi
Mechanism of protein cleavage at asparagine leading to protein–protein cross-links
Biochemical Journal 2019cited by 32position: firstdoi
Cleavage C-terminal to Asp leads to covalent crosslinking of long-lived human proteins
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 2019cited by 28position: middledoi
Spontaneous cross-linking of proteins at aspartate and asparagine residues is mediated via a succinimide intermediate
Biochemical Journal 2018cited by 26position: firstdoi
DehydroalanylGly, a new post translational modification resulting from the breakdown of glutathione
Biochimica et Biophysica Acta (BBA) - General Subjects 2018cited by 8position: firstdoi
Can the Fact That Myelin Proteins Are Old and Break down Explain the Origin of Multiple Sclerosis in Some People?
Journal of Clinical Medicine 2018cited by 8position: lastdoi
The phospholipid composition of the human entorhinal cortex remains relatively stable over 80 years of adult aging
GeroScience 2017cited by 37position: middledoi
Hotspots of age-related protein degradation: the importance of neighboring residues for the formation of non-disulfide crosslinks derived from cysteine
Biochemical Journal 2017cited by 16position: firstdoi
Old Proteins in Man: A Field in its Infancy
Trends in Biochemical Sciences 2016cited by 102position: lastdoi
Amyloid Plaque in the Human Brain Can Decompose from Aβ(1-40/1-42) by Spontaneous Nonenzymatic Processes
Analytical Chemistry 2016cited by 41position: middledoi
Isoaspartic acid is present at specific sites in myelin basic protein from multiple sclerosis patients: could this represent a trigger for disease onset?
Acta Neuropathologica Communications 2016cited by 35position: firstdoi
The etiology of human age-related cataract. Proteins don't last forever
Biochimica et Biophysica Acta (BBA) - General Subjects 2015cited by 114position: lastdoi
Human prefrontal cortex phospholipids containing docosahexaenoic acid increase during normal adult aging, whereas those containing arachidonic acid decrease
Neurobiology of Aging 2015cited by 61position: middledoi
Decreases in Phospholipids Containing Adrenic and Arachidonic Acids Occur in the Human Hippocampus over the Adult Lifespan
Lipids 2015cited by 38position: middledoi
Old proteins and the <scp>A</scp>chilles heel of mass spectrometry. The role of proteomics in the etiology of human cataract
PROTEOMICS - CLINICAL APPLICATIONS 2014cited by 14position: lastdoi
Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?
Experimental Eye Research 2012cited by 32position: middledoi
Molecular signatures of long‐lived proteins: autolytic cleavage adjacent to serine residues
Aging Cell 2012cited by 28position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Roger J.W. Truscott · University of Wollongong24 papers (2012–2025) · 11 papers (2016–2025)Paul L. Else · University of Wollongong5 papers (2015–2022)Sarah E. Hancock · UNSW Sydney5 papers (2015–2022)Todd W. Mitchell · UNSW Sydney5 papers (2015–2022)Zhen Wang · Hebei Normal University3 papers (2018–2021)Zhen Wang · South China Agricultural University3 papers (2018–2019)Brian Lyons · Science Oxford3 papers (2012–2016)Mark J. Raftery · The University of Sydney2 papers (2016–2016)Zhen Wang · Fudan University1 papers (2017–2017)Zhen Wang · Nanjing University1 papers (2021–2021)Larry L. David · Oregon State University1 papers (2012–2012) · 1 papers (2020–2020)Sarah E. Norris · University of Wollongong1 papers (2015–2015) · 1 papers (2019–2019)Michelle Hooi · The University of Adelaide1 papers (2012–2012)Xiaomin Song · Jiangxi Academy of Agricultural Sciences1 papers (2012–2012)Jason D. McArthur · University of Wollongong1 papers (2012–2012)Phillip A. Wilmarth · University of Portland1 papers (2012–2012)J. Andrew Aquilina · University of Wollongong1 papers (2012–2012)
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