Area of research
Pulmonary and Respiratory Medicine · Molecular Biology
Research interest
Research interests include Cystic Fibrosis Research Advances, Neonatal Respiratory Health Research, Ion Transport and Channel Regulation, and Advanced biosensing and bioanalysis techniques.
Transgenic ferret models define pulmonary ionocyte diversity and function
Cystic fibrosis transmembrane conductance regulator dysfunction in platelets drives lung hyperinflammation
Nanomolar-potency ‘co-potentiator’ therapy for cystic fibrosis caused by a defined subset of minimal function CFTR mutants
Combination potentiator (‘co-potentiator’) therapy for CF caused by CFTR mutants, including N1303K, that are poorly responsive to single potentiators
SLC26A3 inhibitor identified in small molecule screen blocks colonic fluid absorption and reduces constipation
Correctors and Potentiators Rescue Function of the Truncated W1282X-Cystic Fibrosis Transmembrane Regulator (CFTR) Translation Product
CFTR Activator Increases Intestinal Fluid Secretion and Normalizes Stool Output in a Mouse Model of Constipation
Inhibitors of pendrin anion exchange identified in a small molecule screen increase airway surface liquid volume in cystic fibrosis