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David‐Alexandre Trégouët

Université de Bordeaux · FR
Area of research
Hematology · Genetics
Research interest
Research interests include Genetic Associations and Epidemiology, Blood Coagulation and Thrombosis Mechanisms, Venous Thromboembolism Diagnosis and Management, and Protease and Inhibitor Mechanisms.
h-index
81
citations
33,513
works
465
NIH funding
primary concept
Medicine
email

Recent publications

Molecular determinants of thrombosis recurrence risk across venous thromboembolism subtypes
Blood 2025cited by 7position: lastdoi
Multipopulation GWAS for venous thromboembolism identifies novel loci followed by experimental validation in zebrafish
Blood Advances 2025cited by 0position: middledoi
Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy
Nature Genetics 2024cited by 53position: middledoi
Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience
Nature Genetics 2024cited by 47position: middledoi
A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels
Blood 2024cited by 22position: middledoi
Integrative Multiomics in the Lung Reveals a Protective Role of Asporin in Pulmonary Arterial Hypertension
Circulation 2024cited by 20position: middledoi
Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease
Nature Medicine 2023cited by 120position: middledoi
Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism
Nature Communications 2023cited by 36position: middledoi
Post-transcriptional control of haemostatic genes: mechanisms and emerging therapeutic concepts in thrombo-inflammatory disorders
Cardiovascular Research 2023cited by 16position: middledoi
Author Correction: Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism
Nature Communications 2023cited by 3position: middledoi
Causal relationships between risk of venous thromboembolism and 18 cancers: a bidirectional Mendelian randomization analysis
International Journal of Epidemiology 2023cited by 2position: middledoi
Causal relationships between risk of venous thromboembolism and 18 cancers: a bidirectional Mendelian randomisation analysis
medRxiv 2023cited by 1position: middledoi
Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors
Circulation 2022cited by 103position: middledoi
APOLD1 loss causes endothelial dysfunction involving cell junctions, cytoskeletal architecture, and Weibel-Palade bodies, while disrupting hemostasis
Haematologica 2022cited by 33position: middledoi
Multi‐phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations
Journal of Thrombosis and Haemostasis 2022cited by 32position: middledoi
Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus
Nature Communications 2022cited by 20position: middledoi
Stroke genetics informs drug discovery and risk prediction across ancestries
Research Square 2022cited by 10position: middledoi
Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors
medRxiv 2022cited by 4position: middledoi
Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25.1 and 22q11.23
European Heart Journal 2021cited by 90position: middledoi
GoldVariants, a resource for sharing rare genetic variants detected in bleeding, thrombotic, and platelet disorders: Communication from the ISTH SSC Subcommittee on Genomics in Thrombosis and Hemostasis
Journal of Thrombosis and Haemostasis 2021cited by 48position: middledoi
Genome-wide analysis identifies novel susceptibility loci for myocardial infarction
European Heart Journal 2020cited by 275position: middledoi
Cerebral small vessel disease genomics and its implications across the lifespan
Nature Communications 2020cited by 207position: middledoi
Single-Cell Study of Two Rat Models of Pulmonary Arterial Hypertension Reveals Connections to Human Pathobiology and Drug Repositioning
American Journal of Respiratory and Critical Care Medicine 2020cited by 100position: middledoi
Whole-Blood RNA Profiles Associated with Pulmonary Arterial Hypertension and Clinical Outcome
American Journal of Respiratory and Critical Care Medicine 2020cited by 72position: middledoi
Whole-exome sequencing identifies rare variants in STAB2 associated with venous thromboembolic disease
Blood 2020cited by 57position: middledoi
Association between ABO haplotypes and the risk of venous thrombosis: impact on disease risk estimation
Blood 2020cited by 45position: middledoi
Genome wide association analysis in dilated cardiomyopathy reveals two new key players in systolic heart failure on chromosome 3p25.1 and 22q11.23
bioRxiv (Cold Spring Harbor Laboratory) 2020cited by 2position: middledoi
Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease
Nature Genetics 2019cited by 255position: middledoi
Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism
Blood 2019cited by 234position: middledoi
Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen
Journal of the American Society of Nephrology 2019cited by 213position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Pierre‐Emmanuel Morange · Inserm6 papers (2012–2017)Stefan Blankenberg · Hochgebirgsklinik Davos6 papers (2012–2016)François Cambien · Unité de recherche sur les maladies cardiovasculaires et métaboliques5 papers (2012–2014)Philipp S. Wild · Papworth Hospital5 papers (2012–2016)Tanja Zeller · Friedrich Schiller University Jena5 papers (2012–2016)Alison H. Goodall · University of Leicester4 papers (2012–2014)Thomas Münzel · Medical Genetics Center4 papers (2012–2013) · 4 papers (2012–2016)Willem H. Ouwehand · University College Hospital4 papers (2012–2021)Karl J. Lackner · Johannes Gutenberg University Mainz3 papers (2012–2016)Panos Deloukas · King Abdulaziz University3 papers (2012–2014)Jeanette Erdmann · Technical University of Applied Sciences Lübeck3 papers (2012–2014)Renate B. Schnabel · Universität Hamburg3 papers (2012–2016)Christian Hengstenberg · Technical University of Munich3 papers (2012–2014)Heribert Schunkert · German Centre for Cardiovascular Research3 papers (2012–2014)Florian Thibord · Utrecht University3 papers (2023–2025)Andreas Ziegler · University Cancer Center Hamburg3 papers (2012–2016)Marine Germain · Bordeaux Population Health3 papers (2013–2020)Maguelonne Roux · Institut Pasteur2 papers (2018–2022)Hermann Brenner · Stanford University2 papers (2023–2023)