Area of research
Immunology · Genetics
Research interest
Research interests include Immune Cell Function and Interaction, T-cell and B-cell Immunology, Chronic Lymphocytic Leukemia Research, and Monoclonal and Polyclonal Antibodies Research.
Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response
Transcriptomes and metabolism define mouse and human MAIT cell populations
Single-cell eQTL analysis of activated T cell subsets reveals activation and cell type–dependent effects of disease-risk variants
COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types
Single-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma
Promoter-interacting expression quantitative trait loci are enriched for functional genetic variants
Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity
Impact of Genetic Polymorphisms on Human Immune Cell Gene Expression
Precursors of human CD4 <sup>+</sup> cytotoxic T lymphocytes identified by single-cell transcriptome analysis
The Immune Checkpoint Modulator OX40 and Its Ligand OX40L in NK-Cell Immunosurveillance and Acute Myeloid Leukemia
17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells
Prognostic relevance of HER2/neu in acute lymphoblastic leukemia and induction of NK cell reactivity against primary ALL blasts by trastuzumab
Neutralization of (NK-cell-derived) B-cell activating factor by Belimumab restores sensitivity of chronic lymphoid leukemia cells to direct and Rituximab-induced NK lysis
An Fc‐optimized NKG2D‐immunoglobulin G fusion protein for induction of natural killer cell reactivity against leukemia
Fc-Optimized NKG2D–Fc Constructs Induce NK Cell Antibody-Dependent Cellular Cytotoxicity against Breast Cancer Cells Independently of HER2/neu Expression Status
Activation-Induced Release of the TNF-Family Member BAFF By NK Cells Facilitates Resistance of Chronic Lymphoid Leukemia Cells to Direct and Rituximab-Induced NK Lysis