Area of research
Immunology · Molecular Biology
Research interest
Research interests include interferon and immune responses, RNA and protein synthesis mechanisms, Inflammasome and immune disorders, and HIV Research and Treatment.
The IFIT2–IFIT3 antiviral complex targets short 5’ untranslated regions on viral mRNAs for translation inhibition
Virology—the path forward
SARS-CoV-2 Uses Nonstructural Protein 16 To Evade Restriction by IFIT1 and IFIT3
Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome
Virology under the Microscope—a Call for Rational Discourse
Structure of LRRK1 and mechanisms of autoinhibition and activation
Antiviral function and viral antagonism of the rapidly evolving dynein activating adaptor NINL
ADP‐ribosyltransferases, an update on function and nomenclature
RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions
Gene conversion generates evolutionary novelty that fuels genetic conflicts
ICTV Virus Taxonomy Profile: Polyomaviridae
A taxonomy update for the family Polyomaviridae
Functional and Evolutionary Analyses Identify Proteolysis as a General Mechanism for NLRP1 Inflammasome Activation
Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals
Rapid Evolution of PARP Genes Suggests a Broad Role for ADP-Ribosylation in Host-Virus Conflicts
Molecular Basis for Specific Recognition of Bacterial Ligands by NAIP/NLRC4 Inflammasomes
Transferred interbacterial antagonism genes augment eukaryotic innate immune function
How a Virus Blocks a Cellular Emergency Access Lane to the Nucleus, STAT!
Identification of an overprinting gene in Merkel cell polyomavirus provides evolutionary insight into the birth of viral genes
Rules of Engagement: Molecular Insights from Host-Virus Arms Races