← back to search

Darren K. McGuire

Saint Luke's Health System · US
Area of research
Endocrinology, Diabetes and Metabolism · Cardiology and Cardiovascular Medicine
Research interest
Originally from Fayetteville, Arkansas, Dr. McGuire holds a bachelor’s degree in chemistry from Hendrix College in Conway. He earned his medical degree at the Johns Hopkins University School of Medicine in Baltimore and completed internal medicine residency training at UT Southwestern. He then received advanced training in cardiology through a fellowship at Duke University in Durham, North Carolina, where he also conducted research for two years, working on a number of large-scale, international clinical trials and registries at the Duke Clinical Research Institute (DCRI). He also earned a master’s degree in health sciences in clinical trials at the Duke University School of Medicine.
h-index
117
citations
106,197
works
794
NIH funding
primary concept
Medicine
email

Recent publications

Oral Semaglutide and Cardiovascular Outcomes in High-Risk Type 2 Diabetes
New England Journal of Medicine 2025cited by 269position: firstdoi
Oral Semaglutide and Cardiovascular Outcomes in People With Type 2 Diabetes, According to SGLT2i Use: Prespecified Analyses of the SOUL Randomized Trial
Circulation 2025cited by 42position: middledoi
SGLT2 Inhibitors and Kidney Outcomes by Glomerular Filtration Rate and Albuminuria
JAMA 2025cited by 26position: middledoi
Effects of Sodium Glucose Cotransporter 2 Inhibitors by Diabetes Status and Level of Albuminuria
JAMA 2025cited by 8position: middledoi
Efficacy and safety of SGLT2 inhibitors with and without glucagon-like peptide 1 receptor agonists: a SMART-C collaborative meta-analysis of randomised controlled trials
The Lancet Diabetes & Endocrinology 2024cited by 125position: middledoi
Metabolic Effects of the SGLT2 Inhibitor Dapagliflozin in Heart Failure Across the Spectrum of Ejection Fraction
Circulation Heart Failure 2024cited by 25position: middledoi
PREVENT Equations: A New Era in Cardiovascular Disease Risk Assessment
Circulation Cardiovascular Quality and Outcomes 2024cited by 22position: middledoi
Dapagliflozin in Myocardial Infarction without Diabetes or Heart Failure
NEJM Evidence 2023cited by 261position: middledoi
Effect of SGLT2 Inhibitors on Cardiovascular Outcomes Across Various Patient Populations
Journal of the American College of Cardiology 2023cited by 130position: middledoi
Early intervention and intensive management of patients with diabetes, cardiorenal, and metabolic diseases
Journal of Diabetes and its Complications 2023cited by 93position: middledoi
Dapagliflozin Improves Heart Failure Symptoms and Physical Limitations Across the Full Range of Ejection Fraction: Pooled Patient-Level Analysis From DEFINE-HF and PRESERVED-HF Trials
Circulation Heart Failure 2023cited by 59position: middledoi
Effect of Sotagliflozin on Early Mortality and Heart Failure-Related Events
JACC Heart Failure 2023cited by 45position: middledoi
Association of Cardiac Biomarkers With Major Adverse Cardiovascular Events in High-risk Patients With Diabetes
JAMA Cardiology 2023cited by 38position: middledoi
Effects of dapagliflozin on hospitalisations in people with type 2 diabetes: post-hoc analyses of the DECLARE-TIMI 58 trial
The Lancet Diabetes & Endocrinology 2023cited by 26position: middledoi
Leveraging electronic health records to streamline the conduct of cardiovascular clinical trials
European Heart Journal 2023cited by 22position: lastdoi
Natriuretic Peptides, Body Mass Index and Heart Failure Risk: Pooled Analyses of SAVOR-TIMI 53, DECLARE-TIMI 58 and CAMELLIA-TIMI 61
European Journal of Heart Failure 2023cited by 9position: middledoi
Sodium-Glucose Cotransporter 2 Inhibitors and Risk of Hyperkalemia in People With Type 2 Diabetes: A Meta-Analysis of Individual Participant Data From Randomized, Controlled Trials
UCL Discovery (University College London) 2022cited by 213position: middle
Dapagliflozin and Prevention of Kidney Disease Among Patients With Type 2 Diabetes: Post Hoc Analyses From the DECLARE-TIMI 58 Trial
Diabetes Care 2022cited by 64position: middledoi
Mediators of ertugliflozin effects on heart failure and kidney outcomes among patients with type 2 diabetes mellitus
Diabetes Obesity and Metabolism 2022cited by 44position: middledoi
Association of Baseline HbA1c With Cardiovascular and Renal Outcomes: Analyses From DECLARE-TIMI 58
Diabetes Care 2022cited by 41position: middledoi
Comparison of Accuracy of Estimation of Cardiac Output by Thermodilution Versus the Fick Method Using Measured Oxygen Uptake
The American Journal of Cardiology 2022cited by 32position: middledoi
Finerenone efficacy in patients with chronic kidney disease, type 2 diabetes and atherosclerotic cardiovascular disease
European Heart Journal - Cardiovascular Pharmacotherapy 2022cited by 26position: middledoi
Efficacy and Safety of Dapagliflozin in Type 2 Diabetes According to Baseline Blood Pressure: Observations From DECLARE-TIMI 58 Trial
Circulation 2022cited by 24position: middledoi
Initial eGFR Changes with Ertugliflozin and Associations with Clinical Parameters: Analyses from the VERTIS CV Trial
American Journal of Nephrology 2022cited by 21position: middledoi
Effect of Dapagliflozin on Hematocrit in Patients With Type 2 Diabetes at High Cardiovascular Risk: Observations From DECLARE-TIMI 58
Diabetes Care 2022cited by 18position: lastdoi
Efficacy and Safety of Dapagliflozin According to Background Use of Cardiovascular Medications in Patients With Type 2 Diabetes
JAMA Cardiology 2022cited by 9position: middledoi
Efficacy and Safety of Dapagliflozin by Baseline Insulin Regimen and Dose: Post Hoc Analyses From DECLARE-TIMI 58
Diabetes Care 2022cited by 2position: middledoi
Effects of ertugliflozin on kidney composite outcomes, renal function and albuminuria in patients with type 2 diabetes mellitus: an analysis from the randomised VERTIS CV trial
Diabetologia 2021cited by 162position: middledoi
Biomarker-Based Risk Prediction of Incident Heart Failure in Pre-Diabetes and Diabetes
JACC Heart Failure 2021cited by 129position: middledoi
The Effect of Dapagliflozin on Albuminuria in DECLARE-TIMI 58
Diabetes Care 2021cited by 108position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Deepak L. Bhatt · Technische Universität Dresden42 papers (2013–2023)Lawrence A. Leiter · St. Michael's Hospital38 papers (2013–2023)Ofri Mosenzon · Hadassah Medical Center34 papers (2013–2023)Stephen D. Wiviott · Brigham and Women's Hospital32 papers (2013–2023)Marc S. Sabatine · Smart Material (Germany)32 papers (2018–2023)Itamar Raz · Thrombolysis in Myocardial Infarction Study Group30 papers (2013–2023)John Wilding · University of Liverpool30 papers (2018–2023)Ingrid Gause‐Nilsson · AstraZeneca (Switzerland)26 papers (2018–2023)Avivit Cahn · Hadassah Medical Center26 papers (2015–2023)Anna Maria Langkilde · AstraZeneca (Brazil)25 papers (2018–2023)Sabina A. Murphy · Boise Bible College22 papers (2018–2023)Erica L. Goodrich · Harvard University18 papers (2018–2023)Thomas A. Zelniker · Thrombolysis in Myocardial Infarction Study Group15 papers (2018–2023)Mikhail Kosiborod · Nagoya University14 papers (2012–2024)Peter A. Johansson · QIMR Berghofer Medical Research Institute14 papers (2018–2023)Ilan Yanuv · Hebrew University of Jerusalem13 papers (2019–2023)Aliza Rozenberg · Hebrew University of Jerusalem13 papers (2019–2023)Silvio E. Inzucchi · Yale University12 papers (2016–2025)Benjamin M. Scirica · Harvard University12 papers (2013–2023)Martin Fredriksson · AstraZeneca (Finland)10 papers (2019–2023)