Area of research
Molecular Biology · Computational Theory and Mathematics
Research interest
Research interests include Protein Structure and Dynamics, Computational Drug Discovery Methods, Bioinformatics and Genomic Networks, and RNA and protein synthesis mechanisms.
Computational design of therapeutic antibodies with improved developability: efficient traversal of binder landscapes and rescue of escape mutations
A structural biology community assessment of AlphaFold2 applications
<scp>DynaMut2</scp>: Assessing changes in stability and flexibility upon single and multiple point missense mutations
Prediction of rifampicin resistance beyond the RRDR using structure-based machine learning approaches
DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability
Tumour risks and genotype–phenotype correlations associated with germline variants in succinate dehydrogenase subunit genes <i>SDHB</i>, <i>SDHC</i> and <i>SDHD</i>
Familial STAG2 germline mutation defines a new human cohesinopathy
Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance
Germline Mutations in the<i>CDKN2B</i>Tumor Suppressor Gene Predispose to Renal Cell Carcinoma
mCSM: predicting the effects of mutations in proteins using graph-based signatures