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Scott J. Diede

Merck & Co., Inc., Rahway, NJ, USA (United States) · US
Area of research
Oncology · Molecular Biology
Research interest
Research interests include Cancer Immunotherapy and Biomarkers, CAR-T cell therapy research, Melanoma and MAPK Pathways, and Cutaneous Melanoma Detection and Management.
h-index
30
citations
6,606
works
90
NIH funding
primary concept
Medicine
email

Recent publications

Efficacy and safety of selumetinib in adults with neurofibromatosis type 1 and symptomatic, inoperable plexiform neurofibromas (KOMET): a multicentre, international, randomised, placebo-controlled, parallel, double-blind, phase 3 study
The Lancet 2025cited by 31position: middledoi
Randomized, double-blind, phase III LEAP-003 study of first-line lenvatinib plus pembrolizumab versus placebo plus pembrolizumab for unresectable or metastatic melanoma
Annals of Oncology 2025cited by 5position: middledoi
Triplet combination treatments with pembrolizumab (pembro) for anti–PD-(L)1–refractory advanced melanoma: Preliminary results of the phase 1/2 KEYMAKER-U02A study.
Journal of Clinical Oncology 2024cited by 4position: middledoi
Randomized, Double-Blind, Placebo-Controlled, Global Phase III Trial of Talimogene Laherparepvec Combined With Pembrolizumab for Advanced Melanoma
Journal of Clinical Oncology 2022cited by 269position: middledoi
Phase II LEAP-004 Study of Lenvatinib Plus Pembrolizumab for Melanoma With Confirmed Progression on a Programmed Cell Death Protein-1 or Programmed Death Ligand 1 Inhibitor Given as Monotherapy or in Combination
Journal of Clinical Oncology 2022cited by 124position: middledoi
1037O MASTERKEY-265: A phase III, randomized, placebo (Pbo)-controlled study of talimogene laherparepvec (T) plus pembrolizumab (P) for unresectable stage IIIB–IVM1c melanoma (MEL)
Annals of Oncology 2021cited by 57position: middledoi
Lenvatinib (len) plus pembrolizumab (pembro) for patients (pts) with advanced melanoma and confirmed progression on a PD-1 or PD-L1 inhibitor: Updated findings of LEAP-004.
Journal of Clinical Oncology 2021cited by 27position: middledoi
KEYNOTE-022 part 3: a randomized, double-blind, phase 2 study of pembrolizumab, dabrafenib, and trametinib in <i>BRAF</i>-mutant melanoma
Journal for ImmunoTherapy of Cancer 2020cited by 171position: middledoi
Long-term safety of pembrolizumab monotherapy and relationship with clinical outcome: A landmark analysis in patients with advanced melanoma
European Journal of Cancer 2020cited by 98position: middledoi
ACCELERATE and European Medicines Agency Paediatric Strategy Forum for medicinal product development of checkpoint inhibitors for use in combination therapy in paediatric patients
European Journal of Cancer 2020cited by 66position: middledoi
Epacadostat plus pembrolizumab versus placebo plus pembrolizumab in patients with unresectable or metastatic melanoma (ECHO-301/KEYNOTE-252): a phase 3, randomised, double-blind study
The Lancet Oncology 2019cited by 930position: middledoi
Pembrolizumab in paediatric patients with advanced melanoma or a PD-L1-positive, advanced, relapsed, or refractory solid tumour or lymphoma (KEYNOTE-051): interim analysis of an open-label, single-arm, phase 1–2 trial
The Lancet Oncology 2019cited by 335position: middledoi
A Phase Ib Study of Pembrolizumab as Second-Line Therapy for Chinese Patients With Advanced or Metastatic Melanoma (KEYNOTE-151)
Translational Oncology 2019cited by 138position: middledoi
Epacadostat (E) plus pembrolizumab (P) versus pembrolizumab alone in patients (pts) with unresectable or metastatic melanoma: Results of the phase 3 ECHO-301/KEYNOTE-252 study.
Journal of Clinical Oncology 2018cited by 134position: middledoi
Oncolytic Virotherapy Promotes Intratumoral T Cell Infiltration and Improves Anti-PD-1 Immunotherapy
Cell 2017cited by 1,474position: middledoi
Three-year overall survival for patients with advanced melanoma treated with pembrolizumab in KEYNOTE-001.
Journal of Clinical Oncology 2016cited by 107position: middledoi
Pembrolizumab (pembro) in combination with dabrafenib (D) and trametinib (T) for <i>BRAF</i>-mutant advanced melanoma: Phase 1 KEYNOTE-022 study.
Journal of Clinical Oncology 2016cited by 49position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Georgina V. Long · ARC Centre of Excellence in Synthetic Biology11 papers (2016–2025)Reinhard Dummer · Kantonsspital Aarau6 papers (2017–2024)Omid Hamid · University Hospital Münster6 papers (2016–2024)Antoni Ribas · UCLA Medical Center5 papers (2016–2020)F. Stephen Hodi · Harvard University5 papers (2016–2021)Caroline Robert · Institut Gustave Roussy5 papers (2016–2024)Ana Arance · Grupo Español de Tumores Neuroendocrinos5 papers (2018–2025)Matteo S. Carlino · Mater Health Services4 papers (2016–2020)Thomas F. Gajewski · University of Illinois Chicago4 papers (2017–2021)Victoria Atkinson · Princess Alexandra Hospital4 papers (2016–2022)Stéphane Dalle · Université Claude Bernard Lyon 13 papers (2018–2024) · 3 papers (2016–2019)Tara C. Mitchell · Penn Center for AIDS Research3 papers (2018–2020)Lev Demidov · Humboldt-Universität zu Berlin3 papers (2018–2021)Jacob Schachter · Sheba Medical Center3 papers (2020–2025)Paolo A. Ascierto · Parker Institute for Cancer Immunotherapy3 papers (2020–2025)Igor Puzanov · Roswell Park Comprehensive Cancer Center3 papers (2017–2021)James Larkin · Trinity College Dublin2 papers (2018–2019)Fernanda Costa Svedman · Pontifícia Universidade Católica do Rio Grande do Sul2 papers (2021–2022)Anthony M. Joshua · Garvan Institute of Medical Research2 papers (2016–2020)