Area of research
Oncology · Molecular Biology
Research interest
Research interests include Bone Metabolism and Diseases, Rheumatoid Arthritis Research and Therapies, CAR-T cell therapy research, and Bone health and treatments.
Mechanisms of osteoclast activation in inflammatory bone loss in rheumatoid arthritis.
From complexity to clarity: aging bone marrow niche in bone and blood regeneration and malignancy.
Deep phenotyping of skin tissue remodeling in patients with systemic sclerosis treated with CD19-CAR T cells
Melanoma bone metastasis-induced osteocyte ferroptosis via the HIF1α-HMOX1 axis.
Metabolic rewiring controlled by HIF-1α tunes IgA-producing B-cell differentiation and intestinal inflammation.
Degeneration and Impaired Resilience of Skull Bone and Hematopoietic Bone Marrow
Oral L-arginine cures arginase 1-dependent chronic cutaneous leishmaniasis by redirecting the T helper cell response
<i>Coxiella burnetii</i>
infects osteoclasts and alters their differentiation and function in a type IV secretion system-dependent manner
CD19 CAR T-Cell Therapy in Autoimmune Disease — A Case Series with Follow-up
Bispecific T cell engager therapy for refractory rheumatoid arthritis
L-arginine metabolism inhibits arthritis and inflammatory bone loss
Acod1-mediated inhibition of aerobic glycolysis suppresses osteoclast differentiation and attenuates bone erosion in arthritis.
Eosinophils preserve bone homeostasis by inhibiting excessive osteoclast formation and activity via eosinophil peroxidase.
Expression of HIF1α in intestinal epithelium restricts arthritis inflammation by inhibiting RIPK3-induced cell death machinery.
Osteocytes support bone metastasis of melanoma cells by CXCL5.
L-arginine metabolism inhibits arthritis and inflammatory bone loss
Macrophages inhibit Coxiella burnetii by the ACOD1-itaconate pathway for containment of Q fever.
Advancing oral immunology for improving oral health
Chronic Systemic Infection of Mice with Leishmania infantum Leads to Increased Bone Mass.
Age-associated B cells contribute to the pathogenesis of rheumatoid arthritis by inducing activation of fibroblast-like synoviocytes via TNF-α-mediated ERK1/2 and JAK-STAT1 pathways
Age-associated B cells contribute to the pathogenesis of rheumatoid arthritis by inducing activation of fibroblast-like synoviocytes via TNF-α-mediated ERK1/2 and JAK-STAT1 pathways.
Estrogen-mediated downregulation of HIF-1α signaling in B lymphocytes influences postmenopausal bone loss
Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity
Macrophages inhibit Coxiella burnetii by the ACOD1‐itaconate pathway for containment of Q fever
Adult alcohol drinking and emotional tone are mediated by neutral sphingomyelinase during development in males
Epithelial HIF2α expression induces intestinal barrier dysfunction and exacerbation of arthritis.
Macrophages inhibit <i>Coxiella burnetii</i> by the ACOD1-itaconate pathway for containment of Q fever
Novel approaches to target the microenvironment of bone metastasis
Regulatory eosinophils induce the resolution of experimental arthritis and appear in remission state of human rheumatoid arthritis
Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects