Area of research
Hepatology · Epidemiology
Research interest
Research interests include Liver Disease and Transplantation, Liver Disease Diagnosis and Treatment, Organ Transplantation Techniques and Outcomes, and Drug-Induced Hepatotoxicity and Protection.
Sotrovimab versus usual care in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not yet time to A-Tango in redefining acute-on-chronic liver failure.
Disordered Bile Acid Metabolism in Alcohol-Related Hepatitis.
Survival With and Without Liver Transplantation in Critically Ill Patients With Cirrhosis: A 20-Year Experience.
Oral-gut microbiome interactions in advanced cirrhosis: characterisation of pathogenic enterotypes and salivatypes, virulence factors and antimicrobial resistance.
Potential therapies for acute-on-chronic liver failure.
Circulating monocytes upregulate CD52 and sustain innate immune function in cirrhosis unless acute decompensation emerges
Perioperative extracorporeal membrane oxygenation in liver transplantation—bridge to transplantation, intraoperative salvage, and postoperative support: outcomes and predictors for survival in a large-volume liver transplant center
Clinical Trial: A Multicentre Randomised Controlled Trial of Carvedilol Versus Variceal Band Ligation in Primary Prevention of Variceal Bleeding in Liver Cirrhosis (CALIBRE Trial).
Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial.
Molnupiravir or nirmatrelvir-ritonavir plus usual care versus usual care alone in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Rapid response teams and recommended ward-based management of acute deterioration: a single-centre retrospective cohort study in an inner-city London (UK) teaching hospital.
Prospective trials support plasma exchange improving survival in acute liver failure - retrospective data analysis should not change clinical practice.
Cell cycle arrest biomarkers for early diagnosis of acute kidney injury after liver transplantation: A prospective cohort study.
Rising rates of sepsis in England: an ecological study.
Is it time to open the doors of the intensive care unit further for patients with alcohol-related liver disease?
Adrenomedullin as an Immunomodulator of CD14<sup>+</sup>MerTK<sup>+</sup> Circulating Monocytes in Liver Failure Syndromes.
Lipidomics-based plasma signature of alcohol-related hepatitis linked to short-term mortality.
Liver transplantation for acute-on-chronic liver failure
Liver transplantation for acute-on-chronic liver failure.
Oral-gut microbiome interactions in advanced cirrhosis: characterisation of pathogenic enterotypes and salivatypes, virulence factors and antimicrobial resistance
Immunopathogenesis of acute on chronic liver failure
Efficacy and Safety of Remdesivir in People With Impaired Kidney Function Hospitalized for COVID-19 Pneumonia: A Randomized Clinical Trial.
Stratified analyses refine association between TLR7 rare variants and severe COVID-19.
Immunopathogenesis of acute on chronic liver failure.
Macrophage activation markers are associated with infection and mortality in patients with acute liver failure.
Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of oesophageal varices: study protocol for a randomised controlled trial.
microRNA associated with hepatocyte injury and systemic inflammation may predict adverse outcomes in cirrhotic patients.
Liver Elastography in Acute Liver Failure: A Pilot Study.
Reply to: "Dysregulation of the LPC-ATX-LPA axis in autoimmune hepatitis is associated with monocyte activation": Autotaxin upregulation in liver failure and the effect on monocyte phenotype and function is a pan-aetiology phenomenon.