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Anthony F. Shields

The Barbara Ann Karmanos Cancer Institute · US
Area of research
Oncology · Cancer Research
Research interest
Research interests include Colorectal Cancer Treatments and Studies, Pancreatic and Hepatic Oncology Research, Cancer Genomics and Diagnostics, and Medical Imaging Techniques and Applications.
h-index
72
citations
19,606
works
768
NIH funding
primary concept
Medicine
email

Recent publications

Tumor Treating Fields With Gemcitabine and Nab-Paclitaxel for Locally Advanced Pancreatic Adenocarcinoma: Randomized, Open-Label, Pivotal Phase III PANOVA-3 Study
Journal of Clinical Oncology 2025cited by 33position: middledoi
Distinct Molecular and Clinical Features of Specific Variants of KRAS Codon 12 in Pancreatic Adenocarcinoma
Clinical Cancer Research 2025cited by 15position: middledoi
Improved Survival With Adjuvant Cyclooxygenase 2 Inhibition in <i>PIK3CA</i>-Activated Stage III Colon Cancer: CALGB/SWOG 80702 (Alliance)
Journal of Clinical Oncology 2024cited by 24position: middledoi
Differential Responses to Immune Checkpoint Inhibitors are Governed by Diverse Mismatch Repair Gene Alterations
Clinical Cancer Research 2024cited by 16position: middledoi
Large-scale analysis of CDH1 mutations defines a distinctive molecular subset with treatment implications in gastric cancer
npj Precision Oncology 2024cited by 8position: middledoi
Tucatinib plus trastuzumab for chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or metastatic colorectal cancer (MOUNTAINEER): a multicentre, open-label, phase 2 study
The Lancet Oncology 2023cited by 238position: middledoi
Mutational analysis of microsatellite-stable gastrointestinal cancer with high tumour mutational burden: a retrospective cohort study
The Lancet Oncology 2023cited by 83position: middledoi
Association of Inflammatory Biomarkers With Survival Among Patients With Stage III Colon Cancer
JAMA Oncology 2023cited by 42position: middledoi
PBRM1 mutations might render a subtype of biliary tract cancers sensitive to drugs targeting the DNA damage repair system
npj Precision Oncology 2023cited by 14position: middledoi
Anticancer Efficacy of KRASG12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of <i>KRAS</i> G12C-Mutant Pancreatic and Lung Cancers
Molecular Cancer Therapeutics 2023cited by 12position: middledoi
Adenoviral-based vaccine promotes neoantigen-specific CD8 <sup>+</sup> T cell stemness and tumor rejection
Science Translational Medicine 2022cited by 67position: middledoi
Effect of Celecoxib vs Placebo Added to Standard Adjuvant Therapy on Disease-Free Survival Among Patients With Stage III Colon Cancer
JAMA 2021cited by 128position: lastdoi
Homologous Recombination Deficiency Alterations in Colorectal Cancer: Clinical, Molecular, and Prognostic Implications
JNCI Journal of the National Cancer Institute 2021cited by 77position: middledoi
Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors
JAMA Oncology 2021cited by 40position: middledoi
Large-scale analysis of KMT2 mutations defines a distinctive molecular subset with treatment implication in gastric cancer
Oncogene 2021cited by 36position: middledoi
Molecular characteristics and clinical outcomes of patients with Neurofibromin 1-altered metastatic colorectal cancer
Oncogene 2021cited by 22position: middledoi
523 Preliminary clinical experience with XmAb20717, a PD-1 x CTLA-4 bispecific antibody, in patients with advanced solid tumors
Regular and Young Investigator Award Abstracts 2021cited by 18position: middledoi
Relationship between <scp>MLH1</scp>, <scp>PMS2</scp>, <scp>MSH2</scp> and <scp>MSH6</scp> gene‐specific alterations and tumor mutational burden in 1057 microsatellite instability‐high solid tumors
International Journal of Cancer 2020cited by 166position: middledoi
The impact of ARID1A mutation on molecular characteristics in colorectal cancer
European Journal of Cancer 2020cited by 75position: middledoi
Clinical Validation of a Machine-learning–derived Signature Predictive of Outcomes from First-line Oxaliplatin-based Chemotherapy in Advanced Colorectal Cancer
Clinical Cancer Research 2020cited by 65position: middledoi
Phase IB/II Randomized Study of FOLFIRINOX Plus Pegylated Recombinant Human Hyaluronidase Versus FOLFIRINOX Alone in Patients With Metastatic Pancreatic Adenocarcinoma: SWOG S1313
Journal of Clinical Oncology 2019cited by 321position: middledoi
The current state of molecular testing in the treatment of patients with solid tumors, 2019
CA A Cancer Journal for Clinicians 2019cited by 260position: middledoi
Duration of Adjuvant Chemotherapy for Stage III Colon Cancer
New England Journal of Medicine 2018cited by 1,118position: middledoi
Safety and pharmacokinetics of MM-302, a HER2-targeted antibody–liposomal doxorubicin conjugate, in patients with advanced HER2-positive breast cancer: a phase 1 dose-escalation study
British Journal of Cancer 2018cited by 120position: middledoi
First-in-Class, First-in-Human Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Patients With Advanced Solid Tumors
Journal of Clinical Oncology 2016cited by 247position: middledoi
Neoadjuvant 5-FU or Capecitabine Plus Radiation With or Without Oxaliplatin in Rectal Cancer Patients: A Phase III Randomized Clinical Trial
JNCI Journal of the National Cancer Institute 2015cited by 327position: middledoi
Repeatability of <sup>18</sup>F-FDG PET/CT in Advanced Non–Small Cell Lung Cancer: Prospective Assessment in 2 Multicenter Trials
Journal of Nuclear Medicine 2015cited by 91position: middledoi
Capecitabine and Oxaliplatin in the Preoperative Multimodality Treatment of Rectal Cancer: Surgical End Points From National Surgical Adjuvant Breast and Bowel Project Trial R-04
Journal of Clinical Oncology 2014cited by 441position: middledoi
Carbohydrate antigen 19‐9 is a prognostic and predictive biomarker in patients with advanced pancreatic cancer who receive gemcitabine‐containing chemotherapy
Cancer 2012cited by 132position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Joanne Xiu · Enzo Life Sciences (United States)8 papers (2020–2025)Philip A. Philip · Henry Ford Health System8 papers (2012–2024)John L. Marshall · Columbia University8 papers (2019–2024)Heinz‐Josef Lenz · Keck Hospital of USC7 papers (2019–2024)Richard M. Goldberg · West Virginia University Hospitals6 papers (2019–2024)W. Michael Korn · Itasca Community College6 papers (2020–2024)Axel Grothey · Campbell Clinic5 papers (2018–2023) · 4 papers (2020–2024)Michael J. Hall · Universidade Nova de Lisboa4 papers (2020–2024)Francesca Battaglin · University of Southern California4 papers (2020–2024)Jeffrey A. Meyerhardt · Harvard University4 papers (2018–2024)Shivani Soni · Caris Life Sciences (United States)4 papers (2020–2024)Hiroyuki Arai · University of Southern California4 papers (2020–2024)Qian Shi · Tongji University4 papers (2018–2024)Eileen M. O’Reilly · Erasmus MC Cancer Institute3 papers (2021–2024)David Spetzler · University of Sopron3 papers (2020–2024)Jimmy J. Hwang · Levine Cancer Institute3 papers (2020–2024)Wu Zhang · University of Southern California3 papers (2020–2023)Mohamed E. Salem · Wake Forest Baptist Comprehensive Cancer Center3 papers (2020–2024)Philip Kuebler · National Cancer Institute3 papers (2021–2024)