Area of research
Surgery · Molecular Biology
Research interest
Research interests include Pancreatic function and diabetes, Metabolism, Diabetes, and Cancer, Diabetes and associated disorders, and Cellular transport and secretion.
Elevated circulating follistatin associates with an increased risk of type 2 diabetes
Oxidative stress and calcium dysregulation by palmitate in type 2 diabetes
Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes
Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes
Sulforaphane improves disrupted ER-mitochondria interactions and suppresses exaggerated hepatic glucose production
Palmitate induces ER calcium depletion and apoptosis in mouse podocytes subsequent to mitochondrial oxidative stress
Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism
TCF7L2 is a master regulator of insulin production and processing
A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets