Area of research
Molecular Biology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Ion Transport and Channel Regulation, Electrolyte and hormonal disorders, Hormonal Regulation and Hypertension, and Ion channel regulation and function.
Defining the vascular niche of human adipose tissue across metabolic states.
Kidney kallikrein-1 contributes to cleavage of γ-ENaC in vivo.
Glutamate transporter xCT is important for cGAS-dependent interferon responses to DNA and to HSV-1
Regulation of the Na-K-2Cl cotransporter NKCC2 by ubiquitylation
Dietary potassium restriction causes hypercalciuria, hypocalcemia, and bone loss in male mice.
Sex-specific remodeling of the human adipose vascular niche in obesity
Genetic deletion of the kidney sodium/proton exchanger-3 (NHE3) does not alter calcium and phosphate balance due to compensatory responses.
Renal Ghrelin-Family GPR39 Receptor and Urinary Concentrating Ability
Excess dietary potassium raises blood pressure in male mice by an aldosterone-dependent increase in ENaC.
Lack of renal NHE1 exacerbates lithium-induced nephrogenic diabetes insipidus.
Urinary EGF Reflects Distal Tubular Mass and Is Associated with Hypertension, Serum Magnesium, and Kidney Outcomes.
Toward Assessment of Tubular Function in Kidney Disease.
Deletion of the prostaglandin EP4 receptor in the kidney tubule of mature mice alters kidney water handling only in males.
Sex differences in renal acid-base regulation.
Association of Urinary PGE2 with Plasma Potassium in Patients with CKD and the General Population.
Single-cell proteomics: a powerful new tool to study kidney cell heterogeneity
How Does Dietary Potassium Influence BP?
Metabolic Communication by SGLT2 Inhibition.
Potassium-Switch Signaling Pathway Dictates Acute Blood Pressure Response to Dietary Potassium.
Guidelines on antibody use in physiology research
Guidelines on antibody use in physiology research.
The Effect of Thiazide Diuretics on Urinary Prostaglandin E2 Excretion and Serum Sodium in the General Population.
Regulation of the water channel aquaporin-2 by cullin E3 ubiquitin ligases.
Urinary Prostaglandin E2 Excretion and the Risk of Cardiovascular and Kidney Disease.
The metalloproteinase PAPP-A is required for IGF-dependent chondrocyte differentiation and organization.
SAM68 directs STING signaling to apoptosis in macrophages.
Inducible deletion of the prostaglandin EP3 receptor in kidney tubules of male and female mice has no major effect on water homeostasis.
Trypanosoma brucei Invariant Surface Glycoprotein 75 Is an Immunoglobulin Fc Receptor Inhibiting Complement Activation and Antibody-Mediated Cellular Phagocytosis.
Editorial: aquaporins in health and disease.
2024 Carl W. Gottschalk Distinguished Lectureship of the American Physiological Society Renal Section.