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Thomas Weber

Spark Therapeutics (United States) · US
Area of research
Genetics · Molecular Biology · gene therapy AAV
Research interest
Research interests include Virus-based gene therapy research, Viral Infections and Immunology Research, Lipid Membrane Structure and Behavior, and Cellular transport and secretion.
h-index
47
citations
9,795
works
147
NIH funding
primary concept
email

Recent publications

Systemic Administration of AAV9-G266A with Focused Ultrasound Enables Robust Brain Transduction with Minimal Liver Transduction.
2026cited by 0position: contributordoi
Natural Adeno-Associated Virus Serotypes and Engineered Adeno-Associated Virus Capsid Variants: Tropism Differences and Mechanistic Insights.
2024cited by 32position: contributordoi
Correction: Lopez-Gordo et al. Natural Adeno-Associated Virus Serotypes and Engineered Adeno-Associated Virus Capsid Variants: Tropism Differences and Mechanistic Insights. <i>Viruses</i> 2024, <i>16</i>, 442.
2024cited by 0position: contributordoi
Selective Anti-AAV Antibody Depletion by Hemapheresis and Immunoadsorption.
2022cited by 2position: contributordoi
Anti-AAV Antibodies in AAV Gene Therapy: Current Challenges and Possible Solutions.
2021cited by 126position: contributordoi
Regulation of the Methylation and Expression Levels of the BMPR2 Gene by SIN3a as a Novel Therapeutic Mechanism in Pulmonary Arterial Hypertension
Circulation 2021cited by 96position: middledoi
Intracellular trafficking of adeno-associated virus (AAV) vectors: challenges and future directions.
2021cited by 93position: contributordoi
Correction: Intracellular trafficking of adeno-associated virus (AAV) vectors: challenges and future directions.
2021cited by 1position: contributordoi
Successful Transduction with AAV Vectors after Selective Depletion of Anti-AAV Antibodies by Immunoadsorption.
2020cited by 61position: contributordoi
Identification of Genes and Pathways Regulated by Lamin A in Heart.
2020cited by 21position: contributordoi
Targeted Gene Delivery through the Respiratory System: Rationale for Intratracheal Gene Transfer.
2019cited by 22position: contributordoi
AAV Vectors for Efficient Gene Delivery to Rodent Hearts.
2019cited by 7position: contributordoi
Pre-existing Anti–Adeno-Associated Virus Antibodies as a Challenge in AAV Gene Therapy
Human Gene Therapy Methods 2013cited by 340position: lastdoi
Quantification of AAV Particle Titers by Infrared Fluorescence Scanning of Coomassie-Stained Sodium Dodecyl Sulfate–Polyacrylamide Gels
Human Gene Therapy Methods 2012cited by 35position: lastdoi

Grants

Constraining methane emissions and sources in the North American Great Lakes system
NSF2524926$848,8012025–2028PIRePORTER
Understanding the drivers and climate sensitivity of open ocean methane emissions to the atmosphere
NSF2241744$294,0922023–2027PIRePORTER
Collaborative Research: Combining models and observations to constrain the marine iron cycle
NSF1658042$221,3902017–2023PIRePORTER
Collaborative Research: Understanding the distribution and biogeochemical role of anaerobic microenvironments in the ocean
NSF1635414$188,7822016–2021PIRePORTER
CAREER: Development of a broadband acoustic system for quantifying the flux of free gas in methane seeps
NSF1352301$690,7852014–2020PIRePORTER

Frequent collaborators

· 6 papers (2019–2024)Estrella Lopez-Gordo · 2 papers (2024–2024)Jalish M. Riyad · Columbia University2 papers (2021–2021)Roger J. Hajjar · Rumah Sakit Umum Pusat Dr. Sardjito2 papers (2012–2013)Jakob A. Joergensen · Icahn School of Medicine at Mount Sinai1 papers (2013–2013)Prabhu Mathiyalagan · Prime University1 papers (2021–2021)Marc Humbert · Médecins Sans Frontières1 papers (2021–2021)Kleopatra Rapti · University Hospital Heidelberg1 papers (2012–2012)Gregory David · New York University1 papers (2021–2021)Shihong Zhang · Medizinische Hochschule Hannover1 papers (2021–2021)R. Michael Linden · Materialise (Belgium)1 papers (2012–2012)Ronald E. Gordon · Icahn School of Medicine at Mount Sinai1 papers (2012–2012)Scot J. Matkovich · Eli Lilly (United States)1 papers (2020–2020)Lahouaria Hadri · Mount Sinai Hospital1 papers (2021–2021)Susmita Sahoo · Cardiovascular Institute Hospital1 papers (2021–2021) · 1 papers (2012–2012)Malik Bisserier · Université Laval1 papers (2021–2021)Peter Dorfmüller · Justus-Liebig-Universität Gießen1 papers (2021–2021)Ali J. Marian · The University of Texas Health Science Center at Houston1 papers (2020–2020)Frédéric Perros · Université Claude Bernard Lyon 11 papers (2021–2021)