Area of research
Immunology · Molecular Biology
Research interest
Research interests include Biology, Virology, Immunology, Antibody, Nanoparticle, and Adjuvant.
Linking vaccine adjuvant mechanisms of action to function
Diverse priming outcomes under conditions of very rare precursor B cells
Vaccination with an mRNA-encoded membrane-bound HIV envelope trimer induces neutralizing antibodies in animal models
Highly functional and prolonged germinal center T follicular helper cell responses are associated with enhanced neutralizing antibody development
Simultaneous induction of multiple classes of broadly neutralizing antibody precursors by combination germline-targeting immunization in nonhuman primates
Vaccination of nonhuman primates elicits a broadly neutralizing antibody lineage targeting a quaternary epitope on the HIV-1 Env trimer
Germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques
Accelerated cGMP production of near-native HIV-1 Env trimers following electroporation transfection and immunogenicity analysis
Two-dose priming immunization amplifies humoral immunity by synchronizing vaccine delivery with the germinal center response
Vaccination with nanoparticles displaying gH/gL from Epstein-Barr virus elicits limited cross-protection against rhesus lymphocryptovirus
Biodegradable lipophilic polymeric mRNA nanoparticles for ligand-free targeting of splenic dendritic cells for cancer vaccination
Controlled lipid self-assembly for scalable manufacturing of next-generation immune stimulating complexes
Biomimetic anisotropic polymeric nanoparticles coated with red blood cell membranes for enhanced circulation and toxin removal
Highly Scalable, Closed‐Loop Synthesis of Drug‐Loaded, Layer‐by‐Layer Nanoparticles
Layer-by-Layer Nanoparticles for Systemic Codelivery of an Anticancer Drug and siRNA for Potential Triple-Negative Breast Cancer Treatment