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Emmanuelle Merquiol

Hebrew University of Jerusalem · IL
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Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Chemistry, Cathepsin, Cathepsin B, Cathepsin D, Cell biology, and Medicine.
h-index
citations
799
works
24
NIH funding
primary concept
email

Recent publications

CD74-Targeted Cathepsin-Inhibitor Antibody–Drug Conjugate Triggers Apoptosis in DLBCL
Cells 2026cited by 1position: middledoi
Development and Application of Small Molecule–Peptide Conjugates as Cathepsin K-Specific Covalent Irreversible Inhibitors in Human Osteoclast and Lung Cancer
JACS Au 2025cited by 7position: middledoi
Novel Nucleus-Oriented Quenched Activity-Based Probes Link Cathepsin Nuclear Localization with Mitosis
ACS Sensors 2025cited by 4position: middledoi
Cathepsin B promotes Aβ proteotoxicity by modulating aging regulating mechanisms
Nature Communications 2024cited by 14position: middledoi
Development and Application of Reversible and Irreversible Covalent Probes for Human and Mouse Cathepsin‐K Activity Detection, Revealing Nuclear Activity
Advanced Science 2024cited by 7position: middledoi
Impact of postharvest processing on the health benefits of durian-derived products
Food Chemistry 2024cited by 2position: middledoi
Challenges in Batch-to-Bed Translation Involving Inflammation-Targeting Compounds in Chronic Epilepsy: The Case of Cathepsin Activity-Based Probes
ACS Omega 2024cited by 2position: middledoi
Differential Effect of Simulated Microgravity on the Cellular Uptake of Small Molecules
Pharmaceutics 2024cited by 1position: middledoi
Improved Cathepsin Probes for Sensitive Molecular Imaging
Molecules 2022cited by 4position: middledoi
IRS1 phosphorylation underlies the non-stochastic probability of cancer cells to persist during EGFR inhibition therapy
Nature Cancer 2021cited by 20position: middledoi
TNFα expression by <i>Porphyromonas gingivalis</i>‐stimulated macrophages relies on Sirt1 cleavage
Journal of Periodontal Research 2021cited by 9position: middledoi
Cathepsins Drive Anti-Inflammatory Activity by Regulating Autophagy and Mitochondrial Dynamics in Macrophage Foam Cells
Cellular Physiology and Biochemistry 2019cited by 28position: middledoi
A Theranostic Cathepsin Activity-Based Probe for Noninvasive Intervention in Cardiovascular Diseases
Theranostics 2019cited by 26position: middledoi
Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation
Molecular & Cellular Proteomics 2019cited by 15position: middledoi
Molecular Imaging of Cancer Using X-ray Computed Tomography with Protease Targeted Iodinated Activity-Based Probes
Nano Letters 2018cited by 78position: middledoi
CT Imaging of Enzymatic Activity in Cancer Using Covalent Probes Reveal a Size-Dependent Pattern
Journal of the American Chemical Society 2018cited by 72position: middledoi
Image-guided surgery using near-infrared Turn-ON fluorescent nanoprobes for precise detection of tumor margins
Theranostics 2018cited by 69position: middledoi
mTORC1 activation in B cells confers impairment of marginal zone microarchitecture by exaggerating cathepsin activity
Immunology 2018cited by 5position: middledoi
Amphiphilic nanocarrier-induced modulation of PLK1 and miR-34a leads to improved therapeutic response in pancreatic cancer
Nature Communications 2017cited by 98position: middledoi
New Role for Interleukin‐13 Receptor α1 in Myocardial Homeostasis and Heart Failure
Journal of the American Heart Association 2017cited by 42position: middledoi
Macrophage-Induced Lymphangiogenesis and Metastasis following Paclitaxel Chemotherapy Is Regulated by VEGFR3
Cell Reports 2016cited by 118position: middledoi
Detecting cathepsin activity in human osteoarthritis via activity-based probes
Arthritis Research & Therapy 2015cited by 64position: middledoi
A novel cysteine cathepsin inhibitor yields macrophage cell death and mammary tumor regression
Oncogene 2015cited by 63position: middledoi
A novel quenched fluorescent activity-based probe reveals caspase-3 activity in the endoplasmic reticulum during apoptosis
Chemical Science 2015cited by 50position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Galia Blum · Hebrew University of Jerusalem22 papers (2015–2026)Yael Ben‐Nun · Hebrew University of Jerusalem10 papers (2015–2019)Tommy Weiss‐Sadan · Hebrew University of Jerusalem7 papers (2015–2025)Gourab Dey · Hebrew University of Jerusalem4 papers (2024–2025) · 4 papers (2015–2025) · 3 papers (2015–2019)Darya Tsvirkun · Hebrew University of Jerusalem3 papers (2018–2019)Reut Sinai‐Turyansky · Hebrew College3 papers (2024–2026) · 3 papers (2015–2019)Hanmant Gaikwad · Hebrew University of Jerusalem3 papers (2018–2022) · 3 papers (2016–2018)Yael Houri‐Haddad · Hebrew University of Jerusalem2 papers (2021–2024)Adi Anaki · Hebrew University of Jerusalem2 papers (2019–2019)Ivan Zlotver · Hebrew University of Jerusalem2 papers (2018–2024)Evalyn Yakobovich · Hebrew University of Jerusalem2 papers (2024–2025)Nikhila Sridharan · Hebrew University of Jerusalem2 papers (2024–2025) · 2 papers (2017–2018)Israel Gotsman · Hadassah Medical Center2 papers (2019–2019) · 2 papers (2015–2018) · 2 papers (2024–2025)
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