Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Chemistry, Cathepsin, Cathepsin B, Cathepsin D, Cell biology, and Medicine.
CD74-Targeted Cathepsin-Inhibitor Antibody–Drug Conjugate Triggers Apoptosis in DLBCL
Development and Application of Small Molecule–Peptide Conjugates as Cathepsin K-Specific Covalent Irreversible Inhibitors in Human Osteoclast and Lung Cancer
Novel Nucleus-Oriented Quenched Activity-Based Probes Link Cathepsin Nuclear Localization with Mitosis
Cathepsin B promotes Aβ proteotoxicity by modulating aging regulating mechanisms
Development and Application of Reversible and Irreversible Covalent Probes for Human and Mouse Cathepsin‐K Activity Detection, Revealing Nuclear Activity
Impact of postharvest processing on the health benefits of durian-derived products
Challenges in Batch-to-Bed Translation Involving Inflammation-Targeting Compounds in Chronic Epilepsy: The Case of Cathepsin Activity-Based Probes
Differential Effect of Simulated Microgravity on the Cellular Uptake of Small Molecules
Improved Cathepsin Probes for Sensitive Molecular Imaging
IRS1 phosphorylation underlies the non-stochastic probability of cancer cells to persist during EGFR inhibition therapy
TNFα expression by <i>Porphyromonas gingivalis</i>‐stimulated macrophages relies on Sirt1 cleavage
Cathepsins Drive Anti-Inflammatory Activity by Regulating Autophagy and Mitochondrial Dynamics in Macrophage Foam Cells
A Theranostic Cathepsin Activity-Based Probe for Noninvasive Intervention in Cardiovascular Diseases
Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation
Molecular Imaging of Cancer Using X-ray Computed Tomography with Protease Targeted Iodinated Activity-Based Probes
CT Imaging of Enzymatic Activity in Cancer Using Covalent Probes Reveal a Size-Dependent Pattern
Image-guided surgery using near-infrared Turn-ON fluorescent nanoprobes for precise detection of tumor margins
mTORC1 activation in B cells confers impairment of marginal zone microarchitecture by exaggerating cathepsin activity
Amphiphilic nanocarrier-induced modulation of PLK1 and miR-34a leads to improved therapeutic response in pancreatic cancer
New Role for Interleukin‐13 Receptor α1 in Myocardial Homeostasis and Heart Failure
Macrophage-Induced Lymphangiogenesis and Metastasis following Paclitaxel Chemotherapy Is Regulated by VEGFR3
Detecting cathepsin activity in human osteoarthritis via activity-based probes
A novel cysteine cathepsin inhibitor yields macrophage cell death and mammary tumor regression
A novel quenched fluorescent activity-based probe reveals caspase-3 activity in the endoplasmic reticulum during apoptosis