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Jacob S. Lewis

University of Wollongong · AU
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Area of research
Molecular Biology · Genetics
Research interest
Research interests include Replisome, DNA replication, Biology, DNA, Primase, and Computational biology.
h-index
citations
737
works
13
NIH funding
primary concept
email

Recent publications

Embracing Heterogeneity: Challenging the Paradigm of Replisomes as Deterministic Machines
Chemical Reviews 2023cited by 8position: firstdoi
Production of long linear DNA substrates with site-specific chemical lesions for single-molecule replisome studies
Methods in enzymology on CD-ROM/Methods in enzymology 2022cited by 4position: middledoi
Replisome bypass of a protein-based R-loop block by Pif1
Proceedings of the National Academy of Sciences 2020cited by 46position: middledoi
A Primase-Induced Conformational Switch Controls the Stability of the Bacterial Replisome
Molecular Cell 2020cited by 26position: middledoi
Tunability of DNA Polymerase Stability during Eukaryotic DNA Replication
Molecular Cell 2019cited by 114position: firstdoi
Spatial and temporal organization of RecA in the Escherichia coli DNA-damage response
eLife 2019cited by 73position: middledoi
Recycling of single-stranded DNA-binding protein by the bacterial replisome
Nucleic Acids Research 2019cited by 65position: middledoi
Nuclease dead Cas9 is a programmable roadblock for DNA replication
Scientific Reports 2019cited by 63position: middledoi
Shining a Spotlight on DNA: Single-Molecule Methods to Visualise DNA
Molecules 2019cited by 34position: middledoi
Design of customizable long linear DNA substrates with controlled end modifications for single-molecule studies
Analytical Biochemistry 2019cited by 27position: lastdoi
Single-molecule visualization of fast polymerase turnover in the bacterial replisome
eLife 2017cited by 129position: firstdoi
Single-molecule visualization of <i>Saccharomyces cerevisiae</i> leading-strand synthesis reveals dynamic interaction between MTC and the replisome
Proceedings of the National Academy of Sciences 2017cited by 66position: firstdoi
The E. coli DNA Replication Fork
˜The œEnzymes 2016cited by 82position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Antoine M. van Oijen · The University of Sydney12 papers (2017–2023)Lisanne M. Spenkelink · University of Wollongong8 papers (2017–2023)Slobodan Jergic · Australian National University7 papers (2016–2022)Nicholas E. Dixon · Australian National University6 papers (2016–2022)S.H. Mueller · University of Wollongong4 papers (2019–2020)Gurleen Kaur · University of Wollongong4 papers (2019–2022)Grant D. Schauer · Colorado State University4 papers (2017–2020) · 2 papers (2017–2019)Elizabeth A. Wood · Jackson Laboratory2 papers (2017–2019)Harshad Ghodke · University of Wollongong2 papers (2019–2019)Zhi‐Qiang Xu · Australian National University2 papers (2019–2020)Enrico Monachino · University of Wollongong2 papers (2017–2020)Mike O’Donnell · Howard Hughes Medical Institute2 papers (2019–2020)Olga Yurieva · Rockefeller University2 papers (2019–2020)Andrew Robinson · The University of Texas at Austin2 papers (2017–2019)Roxanna E. Georgescu · Howard Hughes Medical Institute1 papers (2017–2017)Roger Woodgate · Eunice Kennedy Shriver National Institute of Child Health and Human Development1 papers (2019–2019)Zachary J Romero · University of Arizona1 papers (2019–2019)Matharishwan Naganbabu · Carnegie Mellon University1 papers (2019–2019)Hamish Maynard · University of Wollongong1 papers (2019–2019)
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