Area of research
Molecular Biology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Connective Tissue Growth Factor Research, Angiogenesis and VEGF in Cancer, Pulmonary Hypertension Research and Treatments, and Immune Response and Inflammation.
Mechanical stress-induced connective tissue growth factor plays a critical role in intestinal fibrosis in Crohn's-like colitis.
Connective-Tissue Growth Factor Contributes to TGF-β1-induced Lung Fibrosis.
Driving fibrosis in neuromuscular diseases: Role and regulation of Connective tissue growth factor (CCN2/CTGF).
Role of hypoxia in skeletal muscle fibrosis: Synergism between hypoxia and TGF-β signaling upregulates CCN2/CTGF expression specifically in muscle fibers.
Late Intervention with Radiation-Induced Lung Fibrosis - Comparing Pamrevlumab Anti-CTGF Therapy vs. Pirfenidone vs. Nintedanib as Mono-, Dual- and Triple-therapy Combinations
Towards Better Definition, Quantification and Treatment of Fibrosis in Heart Failure. A Scientific Roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology
Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology.
Denervation-induced skeletal muscle fibrosis is mediated by CTGF/CCN2 independently of TGF-β
Denervation-induced skeletal muscle fibrosis is mediated by CTGF/CCN2 independently of TGF-β.
Connective Tissue Growth Factor Inhibition Enhances Cardiac Repair and Limits Fibrosis After Myocardial Infarction.
Connective tissue growth factor (CTGF) methylation status is associated with prognosis of patients with head and neck squamous cell carcinoma (HNSCC) treated with radiochemotherapy (RCHT): A multicenter study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG).
Oncogene addiction and radiation oncology: effect of radiotherapy with photons and carbon ions in ALK-EML4 translocated NSCLC
Radiation-induced pulmonary gene expression changes are attenuated by the CTGF antibody Pamrevlumab
Anti-connective tissue growth factor (CTGF/CCN2) monoclonal antibody attenuates skin fibrosis in mice models of systemic sclerosis
Effects of CTGF Blockade on Attenuation and Reversal of Radiation-Induced Pulmonary Fibrosis
Synergistic effects of crizotinib and radiotherapy in experimental EML4–ALK fusion positive lung cancer
Connective tissue growth factor regulates cardiac function and tissue remodeling in a mouse model of dilated cardiomyopathy
Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors
Combined Inhibition of CTGF-Signaling and Radiation Therapy in Pancreatic Cancer
Multimodal Therapies for Pancreatic Cancer
Reducing CTGF/CCN2 slows down mdx muscle dystrophy and improves cell therapy