Area of research
Genetics · Oncology
Research interest
Research interests include Pharmacology, Abcg2, P-glycoprotein, Medicine, Pharmacokinetics, and Temozolomide.
ATP-binding cassette transporters restrict drug delivery and efficacy against brain tumors even when blood-brain barrier integrity is lost
Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2
Buparlisib is a brain penetrable pan-PI3K inhibitor
<i>P</i>-Glycoprotein (MDR1/ABCB1) Restricts Brain Penetration of the Bruton’s Tyrosine Kinase Inhibitor Ibrutinib, While Cytochrome P450-3A (CYP3A) Limits Its Oral Bioavailability
ABCB1 Attenuates the Brain Penetration of the PARP Inhibitor AZD2461
The impact of P‐glycoprotein and breast cancer resistance protein on the brain pharmacokinetics and pharmacodynamics of a panel of MEK inhibitors
PI3K–mTOR Pathway Inhibition Exhibits Efficacy Against High-grade Glioma in Clinically Relevant Mouse Models
P-glycoprotein and breast cancer resistance protein restrict the brain penetration of the CDK4/6 inhibitor palbociclib
<scp>ABCB</scp>1 and <scp>ABCG</scp>2 restrict the brain penetration of a panel of novel <scp>EZH</scp>2‐Inhibitors
ABCB1, ABCG2, and PTEN Determine the Response of Glioblastoma to Temozolomide and ABT-888 Therapy
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