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Levi C.M. Buil

Utrecht University · NL
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Area of research
Genetics · Oncology
Research interest
Research interests include Pharmacology, Abcg2, P-glycoprotein, Medicine, Pharmacokinetics, and Temozolomide.
h-index
citations
778
works
10
NIH funding
primary concept
email

Recent publications

ATP-binding cassette transporters restrict drug delivery and efficacy against brain tumors even when blood-brain barrier integrity is lost
Cell Reports Medicine 2021cited by 59position: middledoi
Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2
Neoplasia 2018cited by 134position: middledoi
Buparlisib is a brain penetrable pan-PI3K inhibitor
Scientific Reports 2018cited by 80position: middledoi
<i>P</i>-Glycoprotein (MDR1/ABCB1) Restricts Brain Penetration of the Bruton’s Tyrosine Kinase Inhibitor Ibrutinib, While Cytochrome P450-3A (CYP3A) Limits Its Oral Bioavailability
Molecular Pharmaceutics 2018cited by 27position: middledoi
ABCB1 Attenuates the Brain Penetration of the PARP Inhibitor AZD2461
Molecular Pharmaceutics 2018cited by 24position: middledoi
The impact of P‐glycoprotein and breast cancer resistance protein on the brain pharmacokinetics and pharmacodynamics of a panel of MEK inhibitors
International Journal of Cancer 2017cited by 73position: middledoi
PI3K–mTOR Pathway Inhibition Exhibits Efficacy Against High-grade Glioma in Clinically Relevant Mouse Models
Clinical Cancer Research 2016cited by 81position: middledoi
P-glycoprotein and breast cancer resistance protein restrict the brain penetration of the CDK4/6 inhibitor palbociclib
Investigational New Drugs 2015cited by 84position: middledoi
<scp>ABCB</scp>1 and <scp>ABCG</scp>2 restrict the brain penetration of a panel of novel <scp>EZH</scp>2‐Inhibitors
International Journal of Cancer 2015cited by 72position: middledoi
ABCB1, ABCG2, and PTEN Determine the Response of Glioblastoma to Temozolomide and ABT-888 Therapy
Clinical Cancer Research 2014cited by 144position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Jos H. Beijnen · University of Applied Sciences Utrecht10 papers (2014–2021)Olaf van Tellingen · Utrecht University9 papers (2014–2021)Mark C. de Gooijer · Utrecht University9 papers (2014–2021) · 3 papers (2015–2018)Ping Zhang · Shanghai Institute of Technology3 papers (2015–2018) · 3 papers (2018–2021) · 2 papers (2018–2021)Rolf W. Sparidans · Utrecht University2 papers (2016–2018)Fan Lin · Yunnan University2 papers (2014–2016)Eloy Moreno Roig · Utrecht University1 papers (2014–2014)Willem Boogerd · Utrecht University1 papers (2018–2018)Johannes J.M. Rood · Utrecht University1 papers (2018–2018) · 1 papers (2018–2018)Ping Zhang · Shandong University1 papers (2015–2015)Gang Li · Nanjing Agricultural University1 papers (2015–2015)Thomas Würdinger · Netherlands Institute for Neuroscience1 papers (2014–2014) · 1 papers (2021–2021)Jan H. Beumer · Children's Hospital of Pittsburgh1 papers (2014–2014) · 1 papers (2015–2015) · 1 papers (2016–2016)
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