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Kin Chan

University of Ottawa · CA
Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Cancer Genomics and Diagnostics, DNA Repair Mechanisms, CRISPR and Genetic Engineering, and RNA modifications and cancer.
h-index
45
citations
22,892
works
105
NIH funding
primary concept
Biology
email

Recent publications

Author Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
Nature Genetics 2023cited by 5position: middledoi
Author Correction: Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer
Nature Genetics 2023cited by 1position: middledoi
Mutagenesis induced by protonation of single-stranded DNA is linked to glycolytic sugar metabolism
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis 2023cited by 1position: contributordoi
Analyses of mutational patterns induced by formaldehyde and acetaldehyde reveal similarity to a common mutational signature.
2022cited by 14position: contributordoi
Intrinsic base substitution patterns in diverse species reveal links to cancer and metabolism.
2022cited by 12position: contributordoi
The repertoire of mutational signatures in human cancer
Nature 2020cited by 3,686position: middledoi
Patterns of somatic structural variation in human cancer genomes
Nature 2020cited by 979position: middledoi
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
Nature Genetics 2020cited by 765position: middledoi
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
Nature Genetics 2020cited by 472position: middledoi
Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer
Nature Genetics 2020cited by 305position: middledoi
High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations
Nature Communications 2020cited by 75position: middledoi
Publisher Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
Nature Genetics 2020cited by 13position: middledoi
Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation.
2019cited by 41position: contributordoi
Intrinsic base substitution patterns in diverse species reveal links to cancer and metabolism
2019cited by 2position: contributordoi
An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers
Nature Genetics 2015cited by 433position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

· 5 papers (2019–2023)Natalie Saini · Medical University of South Carolina2 papers (2015–2019)Piotr A. Mieczkowski · University of North Carolina at Chapel Hill1 papers (2015–2015)David J. Kwiatkowski · Harvard University1 papers (2015–2015)Jaegil Kim · GlaxoSmithKline (United States)1 papers (2015–2015)Suzana P. Gelova · KU Leuven1 papers (2019–2019)Cynthia J. Sakofsky · Applied StemCell (United States)1 papers (2019–2019) · 1 papers (2019–2019) · 1 papers (2019–2019)Dmitry A. Gordenin · Brandeis University1 papers (2019–2019)Leszek J. Klimczak · National Cancer Institute1 papers (2019–2019)Gad Getz · Broad Institute1 papers (2015–2015)Ewa P. Malc · University of North Carolina at Chapel Hill1 papers (2015–2015) · 1 papers (2015–2015)Steven A. Roberts · University of Vermont1 papers (2015–2015)David C. Fargo · National Human Genome Research Institute1 papers (2015–2015)Leszek J. Klimczak · National Institute of Environmental Health Sciences1 papers (2015–2015)Dmitry A. Gordenin · National Institute of Environmental Health Sciences1 papers (2015–2015)