Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genetics and Neurodevelopmental Disorders, DNA Repair Mechanisms, Genomic variations and chromosomal abnormalities, and Neuroblastoma Research and Treatments.
The <i>FRA14B</i> common fragile site maps to a region prone to somatic and germline rearrangements within the large <i>GPHN</i> gene
Molecular characterization of common fragile sites as a strategy to discover cancer susceptibility genes
CDK4 inhibition restores G₁-S arrest in<i><i>MYCN</i>-</i>amplified neuroblastoma cells in the context of doxorubicin-induced DNA damage
Low p14ARF expression in neuroblastoma cells is associated with repressed histone mark status, and enforced expression induces growth arrest and apoptosis
Instability at the FRA8I common fragile site disrupts the genomic integrity of the KIAA0146, CEBPD and PRKDC genes in colorectal cancer
HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment
Genomic rearrangements at the FRA2H common fragile site frequently involve non-homologous recombination events across LTR and L1(LINE) repeats