Area of research
Molecular Biology · Physiology
Research interest
Research interests include Cell death mechanisms and regulation, Telomeres, Telomerase, and Senescence, Epigenetics and DNA Methylation, and CAR-T cell therapy research.
Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas
H3K9me3-mediated epigenetic regulation of senescence in mice predicts outcome of lymphoma patients
Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma
Molecular architecture of the DED chains at the DISC: regulation of procaspase-8 activation by short DED proteins c-FLIP and procaspase-8 prodomain
Mathematical modeling of apoptosis
Quantification of High-Molecular Weight Protein Platforms by AQUA Mass Spectrometry as Exemplified for the CD95 Death-Inducing Signaling Complex (DISC)
Stoichiometry of the CD95 Death-Inducing Signaling Complex: Experimental and Modeling Evidence for a Death Effector Domain Chain Model
Cellular FLICE-like inhibitory proteins (c-FLIPs): Fine-tuners of life and death decisions
Systems Biology of Death Receptor-Induced Apoptosis