Area of research
Genetics · Cancer Research
Research interest
Research interests include Glioma Diagnosis and Treatment, Cancer, Hypoxia, and Metabolism, Mitochondrial Function and Pathology, and Advanced NMR Techniques and Applications.
TMET-51. EGFR metabolically suppresses differentiation in H3K27M-mutant diffuse midline glioma
IMG-31. DEUTERIUM METABOLIC IMAGING OF RESPONSE TO PRECISION THERAPY IN BRAF-V600E MUTANT GLIOMAS
BIOM-23. DEUTERIUM METABOLIC IMAGING OF RESPONSE TO PRECISION THERAPY IN BRAF-V600E MUTANT GLIOMAS
Deuterium Metabolic Imaging Reports on TERT Expression and Early Response to Therapy in Cancer
Metabolic imaging detects elevated glucose flux through the pentose phosphate pathway associated with TERT expression in low-grade gliomas
Ferronostics: Measuring Tumoral Ferrous Iron with PET to Predict Sensitivity to Iron-Targeted Cancer Therapies
In vivo detection of γ-glutamyl-transferase up-regulation in glioma using hyperpolarized γ-glutamyl-[1-13C]glycine
PI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival
Clonal expansion and epigenetic reprogramming following deletion or amplification of mutant <i>IDH1</i>
Rapid Conversion of Mutant IDH1 from Driver to Passenger in a Model of Human Gliomagenesis
Mutant IDH1 Expression Drives <i>TERT</i> Promoter Reactivation as Part of the Cellular Transformation Process
<i>IDH1</i> Mutation Induces Reprogramming of Pyruvate Metabolism
Metabolic Reprogramming in Mutant IDH1 Glioma Cells