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B. Frank Gupton

Virginia Commonwealth University · US
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Area of research
Infectious Diseases · Biomedical Engineering
Research interest
Research interests include Chemistry, Human immunodeficiency virus (HIV), Yield (engineering), Combinatorial chemistry, Tenofovir, and Tenofovir alafenamide.
h-index
citations
289
works
11
NIH funding
primary concept
email

Recent publications

Short and Efficient Synthesis of the Antituberculosis Agent Pretomanid from (<i>R</i>)-Glycidol
Organic Process Research & Development 2023cited by 10position: middledoi
Di- <i>tert</i> -butyl Phosphonate Route to the Antiviral Drug Tenofovir
Organic Process Research & Development 2021cited by 13position: middledoi
Six-Step Gram-Scale Synthesis of the Human Immunodeficiency Virus Integrase Inhibitor Dolutegravir Sodium
Organic Process Research & Development 2021cited by 12position: middledoi
Programmed Formation of HCN Oligomers through Organosulfur Catalysis
The Journal of Organic Chemistry 2021cited by 10position: middledoi
An Efficient Synthesis of Tenofovir (PMPA): A Key Intermediate Leading to Tenofovir-Based HIV Medicines
Organic Process Research & Development 2020cited by 21position: lastdoi
An Efficient Synthesis of Tenofovir (PMPA): A Key Intermediate Leading to Tenofovir-Based HIV Medicines
ChemRxiv 2020cited by 2position: lastdoi
An Efficient Synthesis of Tenofovir (PMPA): A Key Intermediate Leading to Tenofovir-Based HIV Medicines
ChemRxiv 2020cited by 1position: lastdoi
Synthesis of 5‐Fluorocytosine Using 2‐Cyano‐2‐fluoroethenolate as a Key Intermediate
European Journal of Organic Chemistry 2019cited by 5position: middledoi
Computationally Assisted Mechanistic Investigation and Development of Pd-Catalyzed Asymmetric Suzuki–Miyaura and Negishi Cross-Coupling Reactions for Tetra-<i>ortho</i>-Substituted Biaryl Synthesis
ACS Catalysis 2018cited by 98position: middledoi
7‐Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir
Angewandte Chemie International Edition 2018cited by 91position: middledoi
Increasing global access to the high-volume HIV drug nevirapine through process intensification
Green Chemistry 2017cited by 35position: lastdoi
Asymmetric One-Pot Synthesis of (3<i>R</i>,3a<i>S</i>,6a<i>R</i>)-Hexahydrofuro[2,3-<i>b</i>]furan-3-ol: A Key Component of Current HIV Protease Inhibitors
The Journal of Organic Chemistry 2016cited by 26position: middledoi
ChemInform Abstract: Improved Synthesis of Mono‐ and Disubstituted 2‐Halonicotinonitriles from Alkylidene Malononitriles.
ChemInform 2014cited by 0position: middledoi
Improved Synthesis of Mono- and Disubstituted 2-Halonicotinonitriles from Alkylidene Malononitriles
Organic Letters 2013cited by 47position: middledoi
Investigating the continuous synthesis of a nicotinonitrile precursor to nevirapine
Beilstein Journal of Organic Chemistry 2013cited by 44position: middledoi
Controlled Synthesis of Silica Capsules: Taming the Reactivity of SiCl4 Using Flow and Chemistry
Journal of Flow Chemistry 2012cited by 6position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

D. Tyler McQuade · Virginia Commonwealth University10 papers (2012–2021)Till Opatz · Johannes Gutenberg University Mainz9 papers (2016–2023)Jule-Phillip Dietz · Virginia Commonwealth University7 papers (2019–2023)Anthony J. Arduengo · Johannes Gutenberg University Mainz5 papers (2016–2020)Flávio S. P. Cardoso · University of Florida4 papers (2020–2023)Brenden P. Derstine · Virginia Commonwealth University4 papers (2019–2020)Ashley R. Longstreet · Massachusetts Institute of Technology4 papers (2012–2014)Andrew C. Yue · Virginia Commonwealth University3 papers (2020–2020)John W. Tomlin · Virginia Commonwealth University3 papers (2020–2020)Cheryl L. Peck · Virginia Commonwealth University3 papers (2020–2020)Rodger W. Stringham · Virginia Commonwealth University3 papers (2020–2020)Brian S. Campbell · Virginia Commonwealth University3 papers (2013–2014)Dinesh J. Paymode · Virginia Commonwealth University3 papers (2020–2020)Dorota Ferenc · Johannes Gutenberg University Mainz3 papers (2019–2021)David Snead · University of Birmingham2 papers (2020–2020)Tobias Lucas · Johannes Gutenberg University Mainz2 papers (2021–2023)David R. Snead · Massachusetts Institute of Technology2 papers (2020–2023) · 2 papers (2020–2020)Timothy F. Jamison · Massachusetts Institute of Technology2 papers (2018–2021)Daniel Rivalti · Virginia Commonwealth University2 papers (2017–2018)
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