Area of research
Organic Chemistry · Inorganic Chemistry
Research interest
Research interests include Catalytic C–H Functionalization Methods, Asymmetric Synthesis and Catalysis, Asymmetric Hydrogenation and Catalysis, and Cyclopropane Reaction Mechanisms.
Photochemical Synthesis of DNA-Encoded 3<i>H</i>-Azepines via Skeletal Editing of Nitroarenes.
Pd-Catalyzed C-H/C-C Cascade Activation for the Synthesis of γ-Lactams.
Pt(IV)-PROTAC Complexes with Synergistic Antitumor Activity and Enhanced Membrane Permeability.
Site-Selective C-H Annulation Reaction via Thianthrenium Salts of Arenes.
The Discovery of a Novel AXL/Triple Angiokinase Inhibitor Based on 6-Chloro-Substituted Indolinone and Side Chain Methyl Substitution Inhibiting Pancreatic Cancer Growth and Metastasis.
Skeletal Editing of Benzene Motif: Photopromoted Transannulation for Synthesis of DNA-Encoded Seven-Membered Rings
Skeletal Editing of Benzene Motif: Photopromoted Transannulation for Synthesis of DNA-Encoded Seven-Membered Rings.
Identification of Chemical Scaffolds That Inhibit the <i>Mycobacterium tuberculosis</i> Respiratory Complex Succinate Dehydrogenase
Transition-metal catalyzed reactions of diazo compounds and <i>N</i>,<i>N</i>-dialkylnitrosoamines
Identification of Chemical Scaffolds That Inhibit the <i>Mycobacterium tuberculosis</i> Respiratory Complex Succinate Dehydrogenase.
Palladium-Catalyzed Regioselective Insertion of Carbenes into γ-C(sp<sup>3</sup>)-H Bonds of Aliphatic Amines.
The synthesis and evaluation of novel ALK inhibitors containing the sulfoxide structure.
Solvent-Controlled Rh(III)-Catalyzed Mono- and Dual Functionalization of Quinolyl Aldoximes with Diazo Compounds.
Anhydrous Carbene Insertion Reactions: A Synthetic Platform for DNA‐Encoded Library
Regioselective <i>ortho</i> C-H insertion of <i>N</i>-nitrosoanilines with naphthoquinone carbenes.
Radical C–H Sulfonation of Arenes: Its Applications on Bioactive and DNA-Encoded Molecules
Radical C-H Sulfonation of Arenes: Its Applications on Bioactive and DNA-Encoded Molecules.
Rh(III)‐Catalyzed C−H Functionalization of <i>N‐</i>Nitrosoanilines with <i>α</i>‐Sulfonylcarbenes
Palladium-Catalyzed Migratory Insertion of Carbenes and C-C Cleavage of Cycloalkanecarboxamides.
Construction of Chiral Quaternary Carbon Stereocenters by Asymmetric Michael Addition of 4‐Amido‐5‐hydroxylpyrazoles to Ethylene Sulfonyl Fluoride
Regioselective conjugate addition of isoxazol-5-ones to ethenesulfonyl fluoride.
Rh(III)-Catalyzed <i>ortho</i> C-H functionalization of aromatic amides with bis(phenylsulfonyl)diazomethane and α-diazosulfones.
Design, Synthesis, and Evaluation of New Mesenchymal-Epithelial Transition Factor (c-Met) Kinase Inhibitors with Dual Chiral Centers.
Crystal structure of 4-(((2-(3-(1-(3-(3-cyanophenyl)-6-oxopyridazin-1(6<i>H</i>)-yl)ethyl)phenyl) pyrimidin-5-yl)oxy)methyl)-1-methylpiperidin-1-ium chloride monohydrate, C<sub>30</sub>H<sub>33</sub>N<sub>6</sub>O<sub>2</sub>Cl
Enhancing the Potential of Miniature-Scale DNA-Compatible Radical Reactions via an Electron Donor-Acceptor Complex and a Reversible Adsorption to Solid Support Strategy.
Highly Enantioselective Addition of <i>N</i>-2,2,2-Trifluoroethylisatin Ketimines to Ethylene Sulfonyl Fluoride.
Enantioselective Addition of Azlactones to Ethylene Sulfonyl Fluoride via Dual Catalysis.
Aromatic C-H Methylation and Other Functionalizations via the Rh(III)-Catalyzed Migratory Insertion of Bis(phenylsulfonyl)carbene and Subsequent Transformations.
Cross‐Dehydrogenative Coupling of Tetrahydroisoquinolines and 2‐Fluoro‐1,3‐benzodithiole‐1,1,3,3‐tetraoxide: A New Synthetic Approach to α‐Monofluoromethyl Tertiary Amines
Diverse functionalization of aryl halides mediated by bis(phenylsulfonyl)methane