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Wolfram Osen

German Cancer Research Center · DE
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Area of research
Immunology · Oncology
Research interest
Research interests include Immunotherapy and Immune Responses, MicroRNA in disease regulation, RNA Interference and Gene Delivery, and CAR-T cell therapy research.
h-index
26
citations
2,427
works
85
NIH funding
primary concept
email

Recent publications

MicroRNAs affecting the susceptibility of melanoma cells to CD8<sup>+</sup> T cell‐mediated cytolysis
Clinical and Translational Medicine 2023cited by 7position: middledoi
Novel microRNAs modulating ecto-5′-nucleotidase expression
Frontiers in Immunology 2023cited by 5position: middledoi
Antigen presentation safeguards the integrity of the hematopoietic stem cell pool
Cell stem cell 2022cited by 81position: middledoi
Carbon ion irradiation plus CTLA4 blockade elicits therapeutic immune responses in a murine tumor model
Cancer Letters 2022cited by 23position: middledoi
SOX9 is a target of miR-134-3p and miR-224-3p in breast cancer cell lines
Molecular and Cellular Biochemistry 2022cited by 11position: middledoi
Adoptively Transferred in vitro-Generated Myeloid-Derived Suppressor Cells Improve T-Cell Function and Antigen-Specific Immunity after Traumatic Lung Injury
Journal of Innate Immunity 2022cited by 5position: middledoi
SOX9 is a Target of miR-134-3p And miR-224-3p in Beast Cancer Cell Lines
Research Square 2021cited by 0position: middledoi
Reprogramming of macrophages employing gene regulatory and metabolic network models
PLoS Computational Biology 2020cited by 69position: middledoi
Photon versus carbon ion irradiation: immunomodulatory effects exerted on murine tumor cell lines
Scientific Reports 2020cited by 22position: middledoi
Measles Vaccines Designed for Enhanced CD8+ T Cell Activation
Viruses 2020cited by 18position: middledoi
Radiation-induced alterations in immunogenicity of a murine pancreatic ductal adenocarcinoma cell line
Scientific Reports 2020cited by 17position: middledoi
Combined prophylactic and therapeutic immune responses against human papillomaviruses induced by a thioredoxin-based L2-E7 nanoparticle vaccine
PLoS Pathogens 2020cited by 16position: middledoi
Cognate Interaction With CD4+ T Cells Instructs Tumor-Associated Macrophages to Acquire M1-Like Phenotype
Frontiers in Immunology 2019cited by 94position: middledoi
Reprogramming of M2-like macrophages to M1-like phenotype by tumor-antigen specific CD4+ T cells
European Journal of Cancer 2019cited by 3position: middledoi
A transplantable tumor model allowing investigation of NY-BR-1-specific T cell responses in HLA-DRB1*0401 transgenic mice
BMC Cancer 2019cited by 1position: middledoi
Controlling the Immune Suppressor: Transcription Factors and MicroRNAs Regulating CD73/NT5E
Frontiers in Immunology 2018cited by 111position: middledoi
MiR-192, miR-200c and miR-17 are fibroblast-mediated inhibitors of colorectal cancer invasion
Oncotarget 2018cited by 31position: middledoi
miR-193b and miR-30c-1* inhibit, whereas miR-576-5p enhances melanoma cell invasion <i>in vitro</i>
Oncotarget 2018cited by 26position: middledoi
Immune Modulatory microRNAs Involved in Tumor Attack and Tumor Immune Escape
JNCI Journal of the National Cancer Institute 2017cited by 153position: middledoi
Generation of murine tumor cell lines deficient in MHC molecule surface expression using the CRISPR/Cas9 system
PLoS ONE 2017cited by 21position: middledoi
miR-339-3p Is a Tumor Suppressor in Melanoma
Cancer Research 2016cited by 97position: middledoi
Replication-Competent Foamy Virus Vaccine Vectors as Novel Epitope Scaffolds for Immunotherapy
PLoS ONE 2015cited by 19position: middledoi
Abstract 1987: Molecular characterization of the breast cancer-associated antigen NY-BR-1
Cancer Research 2015cited by 0position: middledoi
Abstract 5012: Establishment of a transplantable, NY-BR-1 expressing breast cancer model in HLA-transgenic mice
Cancer Research 2015cited by 0position: middledoi
Abstract 3109: A functional microRNA screening approach that identifies microRNAs affecting melanoma cell invasion
Cancer Research 2015cited by 0position: middledoi
Abstract 3154: Identification of CD4+ T cell epitopes specific for the breast cancer associated antigen NY-BR-1
Cancer Research 2015cited by 0position: middledoi
The role of microRNAs in melanoma
European Journal of Cell Biology 2014cited by 41position: middledoi
Identification of NY‐BR‐1‐specific CD4<sup>+</sup> T cell epitopes using HLA‐transgenic mice
International Journal of Cancer 2014cited by 6position: middledoi
Abstract 1259: Murine HLA-restricted CD4+ T cell lines as source of high affinity TCRs specific for the human breast cancer-associated tumor antigen NY-BR-1.
Cancer Research 2013cited by 1position: middledoi
T-Cell Mediated Immune Responses Induced in ret Transgenic Mouse Model of Malignant Melanoma
Cancers 2012cited by 15position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Stefan B. Eichmüller · German Cancer Research Center25 papers (2013–2023)Theresa Kordaß · Heidelberg University9 papers (2016–2023)Adriane Gardyan · Heidelberger Institut für Radioonkologie8 papers (2012–2016)David Eisel · BioNTech (United States)8 papers (2017–2020)Dirk Jäger · German Cancer Research Center5 papers (2014–2020)Inka Zörnig · Heidelberg Engineering (Germany)5 papers (2012–2019)Krishna Das · Innsbruck Medical University5 papers (2015–2019)Rainer König · Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI)4 papers (2018–2020)Elke Dickes · German Cancer Research Center4 papers (2017–2023)Claudia E.M. Weber · Schön Klinik Hamburg Eilbek4 papers (2014–2018)Agnes Hotz-Wagenblatt · Heidelberg University4 papers (2015–2023)Jürgen Debus · NYU Langone Health3 papers (2020–2022)Stefan Rieken · University Medical Center3 papers (2020–2022)Andreas Schneeweiß · NSABP Foundation3 papers (2014–2015)Laura Hartmann · Johannes Gutenberg University Mainz3 papers (2020–2022)Chonglin Luo · Heidelberg University3 papers (2014–2016)Dirk Jaeger · Heidelberg University3 papers (2012–2015)Stefan Eichmueller · German Cancer Research Center3 papers (2012–2015)Tsu-Yang Chao · German Cancer Research Center3 papers (2021–2023)Marcus Oswald · Jena University Hospital2 papers (2018–2020)
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