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Sören Lehmann

Uppsala University · SE
Area of research
Hematology · Genetics
Research interest
Research interests include Acute Myeloid Leukemia Research, Chronic Myeloid Leukemia Treatments, Myeloproliferative Neoplasms: Diagnosis and Treatment, and Acute Lymphoblastic Leukemia research.
h-index
38
citations
7,834
works
172
NIH funding
primary concept
email

Recent publications

Outcomes with intensive treatment for acute myeloid leukemia: an analysis of two decades of data from the HARMONY Alliance
Haematologica 2024cited by 6position: middledoi
Active Immunotherapy with Vididencel As Maintenance Treatment in MRD+ AML Patients in CR1 Results in Strong Anti-Tumor Immune Responses and Durable Long-Term Survival in Patients with an Immune Competent Immune Profile
Blood 2024cited by 2position: middledoi
A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo
Nature Cancer 2023cited by 34position: middledoi
Therapy-related MDS dissected based on primary disease and treatment—a nationwide perspective
Leukemia 2023cited by 18position: middledoi
Prediction model for drug response of acute myeloid leukemia patients
npj Precision Oncology 2023cited by 16position: middledoi
Machine Learning Provides Individualized Prediction of Outcomes after First Complete Remission in Adult AML Patients - Results from the Harmony Platform
Blood 2023cited by 9position: middledoi
Vaccination Using an Allogeneic Leukemia-Derived Dendritic Cell Vaccine, Maintains and Improves Frequencies of Circulating Antigen Presenting Dendritic Cells Correlating with Relapse Free and Overall Survival in AML Patients
Blood 2023cited by 3position: middledoi
Characterization of therapy-related acute myeloid leukemia: increasing incidence and prognostic implications
Haematologica 2022cited by 57position: lastdoi
Long-Term Follow-up of AML Patients Treated Intensively before the Era of Targeted Agents. a Big Data Analysis from the Harmony Collaboration
Blood 2022cited by 1position: middledoi
T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes
Nature Biotechnology 2021cited by 34position: middledoi
Ribonucleotide reductase inhibitors suppress SAMHD1 ara‐CTPase activity enhancing cytarabine efficacy
EMBO Molecular Medicine 2020cited by 59position: middledoi
Chromosomal Abnormalities and Prognosis in <i>NPM1</i>-Mutated Acute Myeloid Leukemia: A Pooled Analysis of Individual Patient Data From Nine International Cohorts
Journal of Clinical Oncology 2019cited by 114position: middledoi
Expression levels of long non-coding RNAs are prognostic for AML outcome
Journal of Hematology & Oncology 2018cited by 101position: middledoi
Mediation analysis reveals common mechanisms of RUNX1 point mutations and RUNX1/RUNX1T1 fusions influencing survival of patients with acute myeloid leukemia
Scientific Reports 2018cited by 17position: middledoi
Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies
Nature Medicine 2017cited by 141position: middledoi
Validation of risk stratification models in acute myeloid leukemia using sequencing-based molecular profiling
Leukemia 2017cited by 71position: middledoi
Comprehensive mapping of the effects of azacitidine on DNA methylation, repressive/permissive histone marks and gene expression in primary cells from patients with MDS and MDS-related disease
Oncotarget 2017cited by 64position: middledoi
Early death rates remain high in high-risk APL: update from the Swedish Acute Leukemia Registry 1997–2013
Leukemia 2017cited by 60position: firstdoi
Increased proportion of mature NK cells is associated with successful imatinib discontinuation in chronic myeloid leukemia
Leukemia 2016cited by 244position: middledoi
An open-label phase I dose-finding study of APR-246 in hematological malignancies
Blood Cancer Journal 2016cited by 85position: lastdoi
Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
New England Journal of Medicine 2014cited by 3,464position: middledoi
Differential methylation in CN-AML preferentially targets non-CGI regions and is dictated by<i>DNMT3A</i>mutational status and associated with predominant hypomethylation of HOX genes
Epigenetics 2014cited by 85position: lastdoi
Tyrosine kinase inhibitor usage, treatment outcome, and prognostic scores in CML: report from the population-based Swedish CML registry
Blood 2013cited by 127position: middledoi
Orphan receptor tyrosine kinases ROR1 and ROR2 in hematological malignancies
Leukemia & lymphoma/Leukemia and lymphoma 2012cited by 82position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

· 5 papers (2013–2022)Stefan Deneberg · Karolinska University Hospital4 papers (2014–2022)Vladimir Lazarević · Lund University3 papers (2016–2022)Henrik Grönberg · Karolinska Institutet3 papers (2014–2018)Gunnar Juliusson · London School of Hygiene & Tropical Medicine3 papers (2016–2022)Johan Lindberg · Science for Life Laboratory3 papers (2014–2018)Mattias Rantalainen · Karolinska Institutet3 papers (2017–2023) · 3 papers (2017–2023)Christer Nilsson · Karolinska University Hospital3 papers (2017–2022) · 2 papers (2023–2024) · 2 papers (2023–2024)Uwe Platzbecker · University College London2 papers (2023–2024)Daniel Klevebring · Karolinska Institutet2 papers (2017–2018) · 2 papers (2017–2022)Eva Hellström‐Lindberg · Karolinska University Hospital2 papers (2017–2023)Mohsen Karimi · Swedish Medical Center2 papers (2014–2017) · 2 papers (2023–2024) · 2 papers (2017–2022)Martin Jädersten · Karolinska Institutet2 papers (2022–2023)Arvind Singh Mer · University of Ottawa2 papers (2017–2018)