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Wei Leong Chew

Agency for Science, Technology and Research · SG
Area of research
Molecular Biology · Genetics
Research interest
Research interests include CRISPR and Genetic Engineering, Virus-based gene therapy research, RNA and protein synthesis mechanisms, and Advanced biosensing and bioanalysis techniques.
h-index
17
citations
2,930
works
39
NIH funding
primary concept
email

Recent publications

Engineering a New Generation of Gene Editors: Integrating Synthetic Biology and AI Innovations
ACS Synthetic Biology 2025cited by 14position: lastdoi
Robust genome and cell engineering via in vitro and in situ circularized RNAs
Nature Biomedical Engineering 2024cited by 21position: middledoi
Embryo and fetal gene editing: Technical challenges and progress toward clinical applications
Molecular Therapy — Methods & Clinical Development 2024cited by 17position: middledoi
Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity
Nature Communications 2021cited by 138position: middledoi
Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy
Nature Communications 2021cited by 91position: middledoi
Translating CRISPR-Cas Therapeutics: Approaches and Challenges
The CRISPR Journal 2020cited by 40position: middledoi
Immune-orthogonal orthologues of AAV capsids and of Cas9 circumvent the immune response to the administration of gene therapy
Nature Biomedical Engineering 2019cited by 123position: middledoi
A multifunctional AAV–CRISPR–Cas9 and its host response
Nature Methods 2016cited by 627position: firstdoi
Engineering and optimising deaminase fusions for genome editing
Nature Communications 2016cited by 76position: middledoi
In vivo gene editing in dystrophic mouse muscle and muscle stem cells
Science 2015cited by 1,038position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Prashant Mali · University of California San Diego5 papers (2016–2024)George M. Church · Harvard University Press3 papers (2015–2016)Nathan Palmer · University of California San Diego3 papers (2019–2024)Elizabeth Y. Wu · Harvard Stem Cell Institute2 papers (2015–2016)Feng Zhang · Broad Institute2 papers (2015–2016)Mohammadsharif Tabebordbar · Broad Institute2 papers (2015–2016)Amy J. Wagers · Harvard University2 papers (2015–2016)Jason Cheng · Harvard Stem Cell Institute2 papers (2015–2016)Kexian Zhu · Harvard University2 papers (2015–2016)Shi Ling Ng · National University of Singapore1 papers (2021–2021)Poh San Lai · National University of Singapore1 papers (2024–2024) · 1 papers (2021–2021)Andrew Portell · Dana-Farber Cancer Institute1 papers (2024–2024)Le Cong · Stanford University1 papers (2015–2015)Irina Solovei · Ludwig-Maximilians-Universität München1 papers (2021–2021)Daniella H. Hock · Westmead Hospital1 papers (2021–2021) · 1 papers (2021–2021)Ashley L. St. John · National University of Singapore1 papers (2021–2021)Chinmay Kumar Mantri · National University of Singapore1 papers (2021–2021)Citra Nurfarah Zaini Mattar · Agency for Science, Technology and Research1 papers (2024–2024)