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Michal Lotem

Hadassah Medical Center · IL
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Area of research
Oncology · Immunology
Research interest
Research interests include Cancer Immunotherapy and Biomarkers, Immunotherapy and Immune Responses, CAR-T cell therapy research, and Melanoma and MAPK Pathways.
h-index
40
citations
18,643
works
198
NIH funding
primary concept
Medicine
email

Recent publications

Interferon Alpha-2a as Treatment for Primary Acquired Melanosis With Atypia and for Primary Acquired Melanosis With Atypia Surrounding Conjunctival Melanoma
American Journal of Ophthalmology 2026cited by 1position: middledoi
HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion
Cell 2025cited by 6position: middledoi
Alternative splicing of modulatory immune receptors in T lymphocytes: a newly identified and targetable mechanism for anticancer immunotherapy
Frontiers in Immunology 2025cited by 6position: lastdoi
Unveiling alternative splicing dynamics in activated T lymphocytes and their implications for immune checkpoint blockade efficacy
iScience 2025cited by 4position: lastdoi
Pembrolizumab versus ipilimumab for advanced melanoma: 10-year follow-up of the phase III KEYNOTE-006 study
Annals of Oncology 2024cited by 88position: middledoi
Targeted inhibition of the IL5 axis for immune checkpoint inhibitors eosinophilic-induced adverse events
Journal for ImmunoTherapy of Cancer 2024cited by 8position: middledoi
Seven-Year Follow-Up of the Phase III KEYNOTE-006 Study: Pembrolizumab Versus Ipilimumab in Advanced Melanoma
Journal of Clinical Oncology 2023cited by 108position: middledoi
Preventing skin toxicities induced by EGFR inhibitors by topically blocking drug-receptor interactions
Science Translational Medicine 2023cited by 11position: middledoi
<scp>Tumor‐infiltrating</scp> lymphocyte transfusion in a patient with treatment refractory triple negative breast cancer
Cancer Reports 2023cited by 3position: middledoi
Dermatological adverse events under programmed cell death‐1 inhibitors as a prognostic marker in metastatic melanoma
Dermatologic Therapy 2022cited by 8position: middledoi
Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): distant metastasis-free survival results from a double-blind, randomised, controlled, phase 3 trial
The Lancet Oncology 2021cited by 382position: middledoi
Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): health-related quality-of-life results from a double-blind, randomised, controlled, phase 3 trial
The Lancet Oncology 2021cited by 72position: middledoi
COVID-19 vaccine as a cause for unilateral lymphadenopathy detected by 18F-FDG PET/CT in a patient affected by melanoma
European Journal of Nuclear Medicine and Molecular Imaging 2021cited by 39position: middledoi
Combined presentation and immunogenicity analysis reveals a recurrent RAS.Q61K neoantigen in melanoma
Journal of Clinical Investigation 2021cited by 35position: middledoi
Alternative Splicing of the Inhibitory Immune Checkpoint Receptor SLAMF6 Generates a Dominant Positive Form, Boosting T-cell Effector Functions
Cancer Immunology Research 2021cited by 19position: lastdoi
Long-term real-world experience with ipilimumab and non-ipilimumab therapies in advanced melanoma: the IMAGE study
BMC Cancer 2021cited by 15position: middledoi
KEYNOTE-022 part 3: a randomized, double-blind, phase 2 study of pembrolizumab, dabrafenib, and trametinib in <i>BRAF</i>-mutant melanoma
Journal for ImmunoTherapy of Cancer 2020cited by 171position: middledoi
Immunotherapy Potentiates the Effect of Chemotherapy in Metastatic Melanoma—A Retrospective Study
Frontiers in Oncology 2020cited by 45position: middledoi
SLAMF6 deficiency augments tumor killing and skews toward an effector phenotype revealing it as a novel T cell checkpoint
eLife 2020cited by 41position: lastdoi
Checkpoint inhibitors: Better outcomes among advanced cutaneous head and neck melanoma patients
PLoS ONE 2020cited by 7position: lastdoi
Pembrolizumab versus ipilimumab in advanced melanoma (KEYNOTE-006): post-hoc 5-year results from an open-label, multicentre, randomised, controlled, phase 3 study
The Lancet Oncology 2019cited by 1,141position: middledoi
Dabrafenib, trametinib and pembrolizumab or placebo in BRAF-mutant melanoma
Nature Medicine 2019cited by 322position: middledoi
Predicting response to pembrolizumab in metastatic melanoma by a new personalization algorithm
Journal of Translational Medicine 2019cited by 19position: middledoi
Neurologic complications of immune checkpoint inhibitors
Journal of Neuro-Oncology 2018cited by 157position: middledoi
Combined Analysis of Antigen Presentation and T-cell Recognition Reveals Restricted Immune Responses in Melanoma
Cancer Discovery 2018cited by 100position: middledoi
4-year survival and outcomes after cessation of pembrolizumab (pembro) after 2-years in patients (pts) with ipilimumab (ipi)-naive advanced melanoma in KEYNOTE-006.
Journal of Clinical Oncology 2018cited by 87position: middledoi
KEYNOTE-022 Part 3: Phase II randomized study of 1L dabrafenib (D) and trametinib (T) plus pembrolizumab (Pembro) or placebo (PBO) for BRAF-mutant advanced melanoma
Annals of Oncology 2018cited by 50position: middledoi
24 Combined analysis of antigen presentation and T cell recognition reveals restricted immune responses in melanoma
ESMO Open 2018cited by 16position: middledoi
Pembrolizumab versus ipilimumab for advanced melanoma: final overall survival results of a multicentre, randomised, open-label phase 3 study (KEYNOTE-006)
The Lancet 2017cited by 1,229position: middledoi
Predictors of responses to immune checkpoint blockade in advanced melanoma
Nature Communications 2017cited by 201position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Jacob Schachter · Sheba Medical Center13 papers (2014–2024)Antoni Ribas · UCLA Medical Center12 papers (2015–2024)Georgina V. Long · ARC Centre of Excellence in Synthetic Biology11 papers (2015–2024)Galit Eisenberg · Hebrew University of Jerusalem10 papers (2013–2025)Ana Arance · Grupo Español de Tumores Neuroendocrinos9 papers (2015–2024)Adil Daud · UCSF Helen Diller Family Comprehensive Cancer Center9 papers (2015–2024)Omid Hamid · University Hospital Münster9 papers (2015–2024)Sharon Merims · Hebrew University of Jerusalem9 papers (2013–2023)Tamar Peretz · Hebrew University of Jerusalem8 papers (2013–2023)James Larkin · Trinity College Dublin8 papers (2015–2024)Matteo S. Carlino · Mater Health Services8 papers (2015–2023)Caroline Robert · Institut Gustave Roussy8 papers (2015–2024)Nageatte Ibrahim · Merck & Co., Inc., Rahway, NJ, USA (United States)8 papers (2015–2019)Catriona M. McNeil · Chris O’Brien Lifehouse8 papers (2015–2024)Laurent Mortier · Inserm7 papers (2015–2021)Teresa M. Petrella · Sunnybrook Health Science Centre7 papers (2016–2024)Jean-Jacques Grob · Centre de Recherche en Cancérologie de Marseille7 papers (2015–2023)Shoshana Frankenburg · Hebrew University of Jerusalem7 papers (2013–2025)Bart Neyns · Belgian Society of Medical Oncology6 papers (2015–2019)Christian U. Blank · Dutch Cancer Society6 papers (2015–2019)
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