Area of research
Infectious Diseases · Epidemiology
Research interest
Research interests include Influenza Virus Research Studies, SARS-CoV-2 and COVID-19 Research, Viral Infections and Vectors, and Viral gastroenteritis research and epidemiology.
Intranasal administration of broad-spectrum macrocyclic peptide inhibitor protects against SARS-CoV-2 Omicron variants.
Structural basis of receptor-binding adaptation of human-infecting H3N8 influenza A virus.
Structural basis of DNA replication fidelity of the Mpox virus.
A nanobody-based therapeutic targeting Nipah virus limits viral escape.
Assembly and breakage of head-to-head double hexamer reveals mpox virus E5-catalyzed DNA unwinding initiation.
Vesicle-associated membrane protein 5 is an intrinsic defense factor for embryonic stem cells against coronaviruses.
Enantiomer-dependent and modification-free DNA matrix as an adjuvant for subunit vaccines against SARS-CoV-2 or pneumococcal infections.
Structural basis for a potent human neutralizing antibody targeting a conserved epitope on the H7 hemagglutinin head.
Dendritic-cell-targeting virus-like particles as potent mRNA vaccine carriers
Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence
Cryo-EM structure of Nipah virus L-P polymerase complex
Evolving roles of glycosylation in the tug-of-war between virus and host
A human monoclonal antibody targeting the monomeric N6 neuraminidase confers protection against avian H5N6 influenza virus infection
Cryo-EM structure of Nipah virus L-P polymerase complex.
NS2 induces an influenza A RNA polymerase hexamer and acts as a transcription to replication switch.
A human monoclonal antibody targeting the monomeric N6 neuraminidase confers protection against avian H5N6 influenza virus infection.
Dual receptor-binding, infectivity, and transmissibility of an emerging H2N2 low pathogenicity avian influenza virus.
Cryo-EM structure of DNA polymerase of African swine fever virus.
African swine fever virus A137R assembles into a dodecahedron cage.
Breaking through the concept barrier to develop broad-spectrum antiviral counter-measures.
Author Correction: NS2 induces an influenza A RNA polymerase hexamer and acts as a transcription to replication switch.
Structure of monkeypox virus DNA polymerase holoenzyme.
Molecular mechanism of de novo replication by the Ebola virus polymerase.
SARS-CoV-2 main protease cleaves MAGED2 to antagonize host antiviral defense.
Longitudinal analysis of antibody dynamics in COVID-19 convalescents reveals neutralizing responses up to 16 months after infection.
Structure of the Ebola virus polymerase complex.
Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes.
A broadly protective antibody that targets the flavivirus NS1 protein.
Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals
Mycobacterium tuberculosis protein kinase G acts as an unusual ubiquitinating enzyme to impair host immunity.