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Donald E. Ayer

University of Utah · US
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Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Genomics and Chromatin Dynamics, Cancer, Hypoxia, and Metabolism, Ubiquitin and proteasome pathways, and Metabolism, Diabetes, and Cancer.
h-index
53
citations
11,964
works
113
NIH funding
primary concept
email

Recent publications

Age-associated decline of MondoA drives cellular senescence through impaired autophagy and mitochondrial homeostasis
Cell Reports 2022cited by 71position: middledoi
The glucose-sensing transcription factor MLX balances metabolism and stress to suppress apoptosis and maintain spermatogenesis
PLoS Biology 2021cited by 25position: middledoi
Protein synthesis inhibitors stimulate MondoA transcriptional activity by driving an accumulation of glucose 6-phosphate
Cancer & Metabolism 2020cited by 16position: lastdoi
Cellular acidosis triggers human MondoA transcriptional activity by driving mitochondrial ATP production
eLife 2019cited by 57position: lastdoi
MondoA drives muscle lipid accumulation and insulin resistance
JCI Insight 2019cited by 38position: middledoi
Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas
Cell Systems 2018cited by 441position: middledoi
Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization
Cell 2018cited by 267position: middledoi
Metabolic reprogramming in triple-negative breast cancer through Myc suppression of TXNIP
Proceedings of the National Academy of Sciences 2015cited by 222position: lastdoi
Deregulated Myc Requires MondoA/Mlx for Metabolic Reprogramming and Tumorigenesis
Cancer Cell 2015cited by 213position: middledoi
Interactions between Myc and MondoA transcription factors in metabolism and tumourigenesis
British Journal of Cancer 2015cited by 63position: lastdoi
Response of <i>BRAF</i> -Mutant Melanoma to BRAF Inhibition Is Mediated by a Network of Transcriptional Regulators of Glycolysis
Cancer Discovery 2014cited by 278position: middledoi
Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs
Nature Cell Biology 2014cited by 156position: middledoi
MondoA-Mlx Transcriptional Activity Is Limited by mTOR-MondoA Interaction
Molecular and Cellular Biology 2014cited by 41position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Blake R. Wilde · Roswell Park Comprehensive Cancer Center6 papers (2014–2020)Mohan R. Kaadige · Translational Genomics Research Institute4 papers (2014–2020)Robert N. Eisenman · Fred Hutch Cancer Center2 papers (2015–2021)Patrick A. Carroll · Seattle University2 papers (2015–2021)Haiwei Gu · Arizona State University2 papers (2015–2021)Daniel Raftery · Center for Cancer Research2 papers (2015–2021)David B. Shackelford · University of California, Los Angeles1 papers (2018–2018)Bryan E. Welm · University of Utah1 papers (2020–2020)Vivek Venkataramani · National Center for Tumor Diseases1 papers (2021–2021)Sivakanthan Kasinathan · Center for Discovery1 papers (2021–2021)Richard A. Scolyer · Westmead Institute for Medical Research1 papers (2014–2014)Antoni Ribas · UCLA Medical Center1 papers (2014–2014)Jay Shendure · Howard Hughes Medical Institute1 papers (2021–2021)Peter Mullen · University of Southern California1 papers (2018–2018)Danijel Djukovic · University of Colorado Boulder1 papers (2015–2015)Gulietta M. Pupo · Hospital Universitario de la Samaritana1 papers (2014–2014)Xianlin Han · The University of Texas Health Science Center at Houston1 papers (2019–2019)Jason Li · Allen Institute1 papers (2014–2014)Liangliang Shen · Chinese Academy of Sciences1 papers (2015–2015)Milica Momcilovic · University of California, Los Angeles1 papers (2018–2018)
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