Area of research
Immunology · Physiology
Research interest
Research interests include Immune Cell Function and Interaction, T-cell and B-cell Immunology, Immunodeficiency and Autoimmune Disorders, and Asthma and respiratory diseases.
RELMβ sets the threshold for microbiome-dependent oral tolerance
Notch3 destabilizes regulatory T cells to drive autoimmune neuroinflammation in multiple sclerosis
Human germline gain-of-function in STAT6: from severe allergic disease to lymphoma and beyond
Analytical challenges in omics research on asthma and allergy: A National Institute of Allergy and Infectious Diseases workshop
Genetic tracing reveals transcription factor Foxp3-dependent and Foxp3-independent functionality of peripherally induced Treg cells
Microbiome, Metabolism, and Immunoregulation of Asthma: An American Thoracic Society and National Institute of Allergy and Infectious Diseases Workshop Report
An embarrassment of riches: RORγt+ antigen-presenting cells in peripheral tolerance
Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections
Single-cell analysis of FOXP3 deficiencies in humans and mice unmasks intrinsic and extrinsic CD4+ T cell perturbations
Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) activity is required for V(D)J recombination
Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee
Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification
A regulatory T cell Notch4–GDF15 axis licenses tissue inflammation in asthma
The Transcription Factor Foxp3 Shapes Regulatory T Cell Identity by Tuning the Activity of trans-Acting Intermediaries
Dominant-negative mutations in human <i>IL6ST</i> underlie hyper-IgE syndrome
Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis
Correction to: Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee
Microbiota therapy acts via a regulatory T cell MyD88/RORγt pathway to suppress food allergy
Report from the National Institute of Allergy and Infectious Diseases workshop on “Atopic dermatitis and the atopic march: Mechanisms and interventions”
Functional reprogramming of regulatory T cells in the absence of Foxp3
Regulation of oral immune tolerance by the microbiome in food allergy
Notch-1 Inhibition Promotes Immune Regulation in Transplantation Via Regulatory T Cell–Dependent Mechanisms
Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4–insufficient subjects
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity
International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee Report on Inborn Errors of Immunity
The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies
Ruxolitinib reverses dysregulated T helper cell responses and controls autoimmunity caused by a novel signal transducer and activator of transcription 1 (STAT1) gain-of-function mutation
Clinical, immunologic, and genetic spectrum of 696 patients with combined immunodeficiency
Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56bright NKG2A+++ Cells, and Yet Display Increased Degranulation and Higher Perforin Content