Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include PI3K/AKT/mTOR signaling in cancer, RNA modifications and cancer, Cancer Genomics and Diagnostics, and Lung Cancer Treatments and Mutations.
Acquired resistance in cancer: towards targeted therapeutic strategies
The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance
Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers
mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT
Inactivation of Capicua drives cancer metastasis
Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma
Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA
mTOR Complex 2 Controls Glycolytic Metabolism in Glioblastoma through FoxO Acetylation and Upregulation of c-Myc
EGFR Mutation-Induced Alternative Splicing of Max Contributes to Growth of Glycolytic Tumors in Brain Cancer
A tale of two approaches: complementary mechanisms of cytotoxic and targeted therapy resistance may inform next-generation cancer treatments
PML mediates glioblastoma resistance to mammalian target of rapamycin (mTOR)-targeted therapies