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Charles A. Parkos

Emory University · US
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Area of research
Immunology and Allergy · Immunology
Research interest
Research interests include Cell Adhesion Molecules Research, Barrier Structure and Function Studies, Immune Response and Inflammation, and Neutrophil, Myeloperoxidase and Oxidative Mechanisms.
h-index
87
citations
25,285
works
418
NIH funding
primary concept
email

Recent publications

Claudin-23 reshapes epithelial tight junction architecture to regulate barrier function
Nature Communications 2023cited by 65position: middledoi
Astrocytic junctional adhesion molecule-A regulates T-cell entry past the glia limitans to promote central nervous system autoimmune attack
Brain Communications 2022cited by 11position: middledoi
Blocking integrin α4β7-mediated CD4 T cell recruitment to the intestine and liver protects mice from western diet-induced non-alcoholic steatohepatitis
Journal of Hepatology 2020cited by 79position: middledoi
Western diet‐induced increase in colonic bile acids compromises epithelial barrier in nonalcoholic steatohepatitis
The FASEB Journal 2020cited by 38position: middledoi
Formyl peptide receptor 2 regulates monocyte recruitment to promote intestinal mucosal wound repair
The FASEB Journal 2019cited by 50position: middledoi
Macrophage-dependent neutrophil recruitment is impaired under conditions of increased intestinal permeability in JAM-A-deficient mice
Mucosal Immunology 2019cited by 30position: lastdoi
Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling
Journal of Clinical Investigation 2017cited by 201position: middledoi
Bioengineering Bacterially Derived Immunomodulants: A Therapeutic Approach to Inflammatory Bowel Disease
ACS Nano 2017cited by 30position: middledoi
Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol
Gastroenterology 2016cited by 322position: middledoi
IL-17A-mediated neutrophil recruitment limits expansion of segmented filamentous bacteria
Mucosal Immunology 2016cited by 142position: middledoi
Neutrophil interactions with epithelial-expressed ICAM-1 enhances intestinal mucosal wound healing
Mucosal Immunology 2016cited by 103position: lastdoi
Norovirus in symptomatic and asymptomatic individuals: cytokines and viral shedding
Clinical & Experimental Immunology 2016cited by 72position: middledoi
Deposition of microparticles by neutrophils onto inflamed epithelium: a new mechanism to disrupt epithelial intercellular adhesions and promote transepithelial migration
The FASEB Journal 2016cited by 66position: middledoi
Annexin A1–containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair
Journal of Clinical Investigation 2015cited by 367position: middledoi
Cutting Edge: IL-36 Receptor Promotes Resolution of Intestinal Damage
The Journal of Immunology 2015cited by 128position: middledoi
Inflammation-induced desmoglein-2 ectodomain shedding compromises the mucosal barrier
Molecular Biology of the Cell 2015cited by 55position: middledoi
Human norovirus infection and the acute serum cytokine response
Clinical & Experimental Immunology 2015cited by 39position: middledoi
HNF4α Regulates Claudin-7 Protein Expression during Intestinal Epithelial Differentiation
American Journal Of Pathology 2015cited by 38position: middledoi
Targeting of Neutrophil Lewis X Blocks Transepithelial Migration and Increases Phagocytosis and Degranulation
American Journal Of Pathology 2015cited by 36position: lastdoi
Proinflammatory cytokine-induced tight junction remodeling through dynamic self-assembly of claudins
Molecular Biology of the Cell 2014cited by 132position: middledoi
JAM-related proteins in mucosal homeostasis and inflammation
Seminars in Immunopathology 2014cited by 113position: lastdoi
Interleukin‐4 and interleukin‐13 compromise the sinonasal epithelial barrier and perturb intercellular junction protein expression
International Forum of Allergy & Rhinology 2014cited by 110position: middledoi
Galectin-3 Regulates Desmoglein-2 and Intestinal Epithelial Intercellular Adhesion
Journal of Biological Chemistry 2014cited by 57position: middledoi
Junctional Adhesion Molecule A Promotes Epithelial Tight Junction Assembly to Augment Lung Barrier Function
American Journal Of Pathology 2014cited by 45position: middledoi
Epithelial adhesion molecules and the regulation of intestinal homeostasis during neutrophil transepithelial migration
Tissue Barriers 2014cited by 38position: lastdoi
<i>Trans-</i>dimerization of JAM-A regulates Rap2 and is mediated by a domain that is distinct from the<i>cis-</i>dimerization interface
Molecular Biology of the Cell 2014cited by 37position: lastdoi
IFNγ-induced suppression of β-catenin signaling: evidence for roles of Akt and 14.3.3ζ
Molecular Biology of the Cell 2014cited by 20position: middledoi
The Role of Polymorphonuclear Leukocyte Trafficking in the Perpetuation of Inflammation During Inflammatory Bowel Disease
Inflammatory Bowel Diseases 2013cited by 153position: lastdoi
JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function
Molecular Biology of the Cell 2013cited by 127position: lastdoi
Transmigrated neutrophils in the intestinal lumen engage ICAM-1 to regulate the epithelial barrier and neutrophil recruitment
Mucosal Immunology 2013cited by 124position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Asma Nusrat · Michigan United18 papers (2012–2023)Asma Nusrat · University of Michigan–Ann Arbor18 papers (2012–2015)Ronen Sumagin · Northwestern University12 papers (2013–2017)Roland Hilgarth · University of Michigan11 papers (2012–2019)Timothy L. Denning · Georgia State University8 papers (2012–2019)Porfirio Nava · Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional7 papers (2012–2016)Hikaru Nishio · Emory University6 papers (2015–2019)Jennifer Brazil · Michigan United6 papers (2013–2023)Giovanna Leoni · Ludwig-Maximilians-Universität München6 papers (2012–2017)Andrew S. Neish · Emory University6 papers (2012–2019)Stefan Koch · Linköping University6 papers (2012–2014)Miguel Quirós · University of Michigan5 papers (2014–2019)Mingli Feng · Tianjin University5 papers (2013–2017)Anny‐Claude Luissint · Unit of Virus Host Cell Interactions5 papers (2014–2023)Michael Koval · Emory University4 papers (2014–2023)Óscar Medina‐Contreras · Hospital General de México4 papers (2012–2015)Nancy A. Louis · Emory University4 papers (2012–2015)Bénédicte Fournier · Assistance Publique – Hôpitaux de Paris4 papers (2012–2012)Kyle A. Den Beste · Orlando Immunology Center4 papers (2012–2014)Ryuta Kamekura · Sapporo Medical University4 papers (2013–2015)
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