Area of research
Epidemiology · Hepatology
Research interest
Research interests include Hepatitis B virus, Virology, Biology, Innate immune system, Immunology, and cccDNA.
TRIM proteins: A ‘swiss army knife’ of antiviral immunity
Hepatitis D virus interferes with hepatitis B virus RNA production via interferon-dependent and -independent mechanisms
EGF receptor modulates HEV entry in human hepatocytes
Molecular elucidation of drug-induced abnormal assemblies of the hepatitis B virus capsid protein by solid-state NMR
Peripheral natural killer cells in chronic hepatitis B patients display multiple molecular features of T cell exhaustion
RNA helicase DDX5 enables STAT1 mRNA translation and interferon signalling in hepatitis B virus replicating hepatocytes
Hypoxia‐Inducible Factor 1 Alpha–Mediated RelB/APOBEC3B Down‐regulation Allows Hepatitis B Virus Persistence
Interplay Between CMGC Kinases Targeting SR Proteins and Viral Replication: Splicing and Beyond
Evidence for long-term association of virion-delivered HBV core protein with cccDNA independently of viral protein production
Control of APOBEC3B induction and cccDNA decay by NF-κB and miR-138-5p
Inducers of the NF-κB pathways impair hepatitis delta virus replication and strongly decrease progeny infectivity in vitro
How to get away with liver innate immunity? A viruses’ tale
COVID-19: Discovery, diagnostics and drug development
Restoration of RNA helicase DDX5 suppresses hepatitis B virus (HBV) biosynthesis and Wnt signaling in HBV-related hepatocellular carcinoma
Hepatitis B virus Core protein nuclear interactome identifies SRSF10 as a host RNA-binding protein restricting HBV RNA production
A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control
Oxygenation and miR138-5 p act as rheostats in APOBEC3B-mediated Hepatitis B Virus control
Hepatitis B virus-induced modulation of liver macrophage function promotes hepatocyte infection
Toll-like receptor 3 downregulation is an escape mechanism from apoptosis during hepatocarcinogenesis
Circulating and Hepatic BDCA1+, BDCA2+, and BDCA3+ Dendritic Cells Are Differentially Subverted in Patients With Chronic HBV Infection
Mechanisms of Lymphotoxin-beta Receptor Agonization induced upregulation of the anti-HBV host restriction factor APOBEC3B
Novel Potent Capsid Assembly Modulators Regulate Multiple Steps of the Hepatitis B Virus Life Cycle
Hepatitis B Virus Evasion From Cyclic Guanosine Monophosphate–Adenosine Monophosphate Synthase Sensing in Human Hepatocytes
Direct antiviral properties of TLR ligands against HBV replication in immune-competent hepatocytes
Characterization of Pattern Recognition Receptor Expression and Functionality in Liver Primary Cells and Derived Cell Lines
Liver macrophages: Friend or foe during hepatitis B infection?
Hepatitis B and hepatitis D virus infections in the Central African Republic, twenty-five years after a fulminant hepatitis outbreak, indicate continuing spread in asymptomatic young adults
Hepatitis B Virus Blocks the CRE/CREB Complex and Prevents TLR9 Transcription and Function in Human B Cells
The diverse functions of the hepatitis B core/capsid protein (HBc) in the viral life cycle: Implications for the development of HBc-targeting antivirals
Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism