Area of research
Immunology · Epidemiology
Research interest
Research interests include Immune Cell Function and Interaction, Immunotherapy and Immune Responses, T-cell and B-cell Immunology, and Liver Disease Diagnosis and Treatment.
Integrative omics and phase IIa clinical trial identify TNF as key node in autoimmune hepatitis
High-throughput chemical proteomics workflow for profiling protein citrullination dynamics.
Precursors of exhausted T cells are pre-emptively formed in acute infection.
Polyunsaturated fatty acid-induced metabolic exhaustion and ferroptosis impair the anti-tumour function of MAIT cells in MASLD
Polyunsaturated fatty acid-induced metabolic exhaustion and ferroptosis impair the anti-tumour function of MAIT cells in MASLD.
Prediction of COVID-19 disease progression by multiparametric analysis of circulating extracellular vesicles with flow cytometry.
High-throughput chemical proteomics workflow for profiling protein citrullination dynamics
PGE2 limits effector expansion of tumour-infiltrating stem-like CD8+ T cells
PGE<sub>2</sub> limits effector expansion of tumour-infiltrating stem-like CD8<sup>+</sup> T cells.
A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection
A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection.
Attenuated effector T cells are linked to control of chronic HBV infection
Decrypting the molecular basis of cellular drug phenotypes by dose-resolved expression proteomics
Attenuated effector T cells are linked to control of chronic HBV infection.
Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation.
Receptor transfer between immune cells by autoantibody-enhanced, CD32-driven trogocytosis is hijacked by HIV-1 to infect resting CD4 T cells
Role of immune responses in the development of NAFLD-associated liver cancer and prospects for therapeutic modulation
Role of immune responses in the development of NAFLD-associated liver cancer and prospects for therapeutic modulation.
Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling
Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling.
Activation of CD4 T cells during prime immunization determines the success of a therapeutic hepatitis B vaccine in HBV-carrier mouse models
Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development
Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury.
Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8 <sup>+</sup> T cells
TIMP-1 is a novel ligand of Amyloid Precursor Protein and triggers a proinflammatory phenotype in human monocytes.
Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development.
Hepatitis B Virus Targets Lipid Transport Pathways to Infect Hepatocytes
Potent high-avidity neutralizing antibodies and T cell responses after COVID-19 vaccination in individuals with B cell lymphoma and multiple myeloma.
mRNA 3'UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus.
Inflammatory Cues Direct Skin-Resident Type 1 Innate Lymphoid Cells to Adopt a Psoriasis-Promoting Identity.