Area of research
Immunology · Oncology
Research interest
Research interests include Immune Cell Function and Interaction, Immunotherapy and Immune Responses, T-cell and B-cell Immunology, and Cancer Immunotherapy and Biomarkers.
PD-1 blockade increases the self-renewal of stem-like CD8 T cells to compensate for their accelerated differentiation into effectors
Characteristics and anatomic location of PD-1 <sup>+</sup> TCF1 <sup>+</sup> stem-like CD8 T cells in chronic viral infection and cancer
PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program
Functional HPV-specific PD-1+ stem-like CD8 T cells in head and neck cancer
Tumor-draining lymph node is important for a robust abscopal effect stimulated by radiotherapy
PD-1+ stemlike CD8 T cells are resident in lymphoid tissues during persistent LCMV infection
Re-defining T-Cell Exhaustion: Subset, Function, and Regulation
An intra-tumoral niche maintains and differentiates stem-like CD8 T cells
Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection
Epigenetic signature of PD-1+ TCF1+ CD8 T cells that act as resource cells during chronic viral infection and respond to PD-1 blockade
CD8 T Cell Exhaustion in Chronic Infection and Cancer: Opportunities for Interventions
Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy