Area of research
Molecular Biology
Research interest
Research interests include Genomics and Chromatin Dynamics, Heat shock proteins research, Ubiquitin and proteasome pathways, and Protein Structure and Dynamics.
CROPseq-multi: a universal solution for multiplexed perturbation in high-content pooled CRISPR screens
An HSF1–JMJD6–HSP feedback circuit promotes cell adaptation to proteotoxic stress
A universal deep-learning model for zinc finger design enables transcription factor reprogramming
Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4
HSF2 cooperates with HSF1 to drive a transcriptional program critical for the malignant state
A conformational switch driven by phosphorylation regulates the activity of the evolutionarily conserved SNARE Ykt6
Functional characterization of a PROTAC directed against BRAF mutant V600E
Function, evolution, and structure of J-domain proteins
An inter‐species protein–protein interaction network across vast evolutionary distance
Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders
A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways
Genome-Wide Prediction and Validation of Peptides That Bind Human Prosurvival Bcl-2 Proteins
Genome-Wide Prediction and Validation of Peptides That Bind Human Prosurvival Bcl-2 Proteins
2014cited by 0position: middle
DNA-Binding Specificities of Human Transcription Factors
Widespread Regulation of Translation by Elongation Pausing in Heat Shock
Mapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition
Chaperones as thermodynamic sensors of drug-target interactions reveal kinase inhibitor specificities in living cells
Chaperones as thermodynamic sensors of drug-target interactions reveal kinase inhibitor specificities in living cells
2013cited by 3position: first
Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition
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