Area of research
Molecular Biology · Oncology
Research interest
Research interests include CRISPR and Genetic Engineering, RNA and protein synthesis mechanisms, Colorectal Cancer Treatments and Studies, and Bacteriophages and microbial interactions.
Digestive cancers: mechanisms, therapeutics and management
Combined MEK and PARP inhibition enhances radiation response in rectal cancer
Structured Magnetic Resonance Imaging Assessment Improves Diagnosis of Pathological Complete Response in Rectal Cancer after Neoadjuvant Chemoradiation
Clinical impact of panel gene sequencing on therapy of advanced cancers of the digestive system: a retrospective, single center study
Analysis of cell free DNA to predict outcome to bevacizumab therapy in colorectal cancer patients
Functional status and quality of life in older patients with advanced esophageal squamous cell cancer receiving second-line nivolumab ± ipilimumab therapy: A post hoc analysis of the phase 2, multicenter RAMONA study
An organoid platform reveals MEK-PARP co-targeting to enhance radiation response in rectal cancer
Perioperative Atezolizumab Plus Fluorouracil, Leucovorin, Oxaliplatin, and Docetaxel for Resectable Esophagogastric Cancer: Interim Results From the Randomized, Multicenter, Phase II/III DANTE/IKF-s633 Trial
The Roles of Secreted Wnt Ligands in Cancer
The drug-induced phenotypic landscape of colorectal cancer organoids
Cross-Talk between p53 and Wnt Signaling in Cancer
Second-line therapy with nivolumab plus ipilimumab for older patients with oesophageal squamous cell cancer (RAMONA): a multicentre, open-label phase 2 trial
Targeting euchromatic histone lysine methyltransferases sensitizes colorectal cancer to histone deacetylase inhibitors
Personalized functional profiling using <i>ex-vivo</i> patient-derived spheroids points out the potential of an antiangiogenic treatment in a patient with a metastatic lung atypical carcinoid
Sequential Geriatric Assessment in Older Patients with Colorectal Cancer during Chemotherapy: Subgroup Analysis of a Prospective, Multicenter Study EpiReal 75
Neglected geriatric assessment and overtreatment of older patients with pancreatic cancer - Results from a prospective phase IV clinical trial
Prognostic Cancer Gene Expression Signatures: Current Status and Challenges
PPARγ induces PD-L1 expression in MSS+ colorectal cancer cells
Pooled In Vitro and In Vivo CRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids
Multi‐omics integration identifies a selective vulnerability of colorectal cancer subtypes to <scp>YM155</scp>
Cancer-Associated Mutations in Normal Colorectal Mucosa Adjacent to Sporadic Neoplasia
Cancer-associated mutations in normal colorectal mucosa adjacent to sporadic neoplasia
MEK inhibitors activate Wnt signalling and induce stem cell plasticity in colorectal cancer
The drug-induced phenotypic landscape of colorectal cancer organoids
Detection of mutational patterns in cell‐free <scp>DNA</scp> of colorectal cancer by custom amplicon sequencing
Pharmacological treatment of hepatocellular carcinoma with cavoatrial tumor thrombus – case series and literature review
The effect of gender-specific invitation letters on utilization of colorectal cancer screening
MEK inhibitors activate Wnt signalling and induce stem cell plasticity in colorectal cancer
Mikroskopiebasiertes Hochdurchsatz-Wirkstoffscreening mit Organoiden zeigt wirkstoffinduzierte Phänotypen und individuelles Ansprechen
CRISPR/Cas9 for cancer research and therapy