Claudia Sissi

Vimentin binds to G-quadruplex repeats found at telomeres and gene promoters

G-Quadruplex Modulation of SP1 Functional Binding Sites at the KIT Proximal Promoter

A Gold Nanoparticle Nanonuclease Relying on a Zn(II) Mononuclear Complex

Targeting topoisomerase II with trypthantrin derivatives: Discovery of 7-((2-(dimethylamino)ethyl)amino)indolo[2,1-b]quinazoline-6,12-dione as an antiproliferative agent and to treat cancer

Coumarins from<i>Magydaris pastinacea</i>as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation

Novel, Potent, and Druglike Tetrahydroquinazoline Inhibitor That Is Highly Selective for Human Topoisomerase II α over β

Polymorphism of human telomeric quadruplexes with drugs: a multi-technique biophysical study

Ferulic Acid Esters and Withanolides: In Search of <i>Withania somnifera</i> GABA_A Receptor Modulators

Targeting multiple G-quadruplex–forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives

Two-quartet kit* G-quadruplex is formed via double-stranded pre-folded structure

<i>In Silico</i> Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes

Coexistence of two main folded G-quadruplexes within a single G-rich domain in the EGFR promoter

Characterization of G4–G4 Crosstalk in the <i>c-KIT</i> Promoter Region

Pharmacophore Hybridization To Discover Novel Topoisomerase II Poisons with Promising Antiproliferative Activity

G-quadruplexes in human promoters: A challenge for therapeutic applications

Screening of candidate G-quadruplex ligands for the human <i>c-KIT</i> promotorial region and their effects in multiple <i>in-vitro</i> models

Quinolino[3,4- b ]quinoxalines and pyridazino[4,3- c ]quinoline derivatives: Synthesis, inhibition of topoisomerase IIα, G-quadruplex binding and cytotoxic properties

Optimized Virtual Screening Workflow for the Identification of Novel G-Quadruplex Ligands

Water-soluble isoindolo[2,1-a]quinoxalin-6-imines: In vitro antiproliferative activity and molecular mechanism(s) of action

Aza-isoindolo and isoindolo-azaquinoxaline derivatives with antiproliferative activity

Macrocyclic naphthalene diimides as G-quadruplex binders

An optimized polyamine moiety boosts the potency of human type II topoisomerase poisons as quantified by comparative analysis centered on the clinical candidate F14512

Pt-based drugs: the spotlight will be on proteins

Aryl ethynyl anthraquinones: a useful platform for targeting telomeric G-quadruplex structures

Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches

Platinum-based drugs and proteins: Reactivity and relevance to DNA adduct formation

Exploring the Chemical Space of G-Quadruplex Binders: Discovery of a Novel Chemotype Targeting the Human Telomeric Sequence

Spectroscopic, Molecular Modeling, and NMR-Spectroscopic Investigation of the Binding Mode of the Natural Alkaloids Berberine and Sanguinarine to Human Telomeric G-Quadruplex DNA

Hybrid ligand–alkylating agents targeting telomeric G-quadruplex structures

Autophagy acts as a safeguard mechanism against G-quadruplex ligand-mediated DNA damage