Area of research
Molecular Biology · Physiology
Research interest
Research interests include Adipose Tissue and Metabolism, Estrogen and related hormone effects, Peroxisome Proliferator-Activated Receptors, and Adipokines, Inflammation, and Metabolic Diseases.
The time is now: accounting for time-of-day effects to improve reproducibility and translation of metabolism research
The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits
Novel Roles for the Transcriptional Repressor E4BP4 in Both Cardiac Physiology and Pathophysiology
Cardiomyocyte-specific disruption of the circadian BMAL1–REV-ERBα/β regulatory network impacts distinct miRNA species in the murine heart
Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD+ biosynthesis and sustain cardiac function
Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner
Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity
A noncanonical PPARγ/RXRα-binding sequence regulates leptin expression in response to changes in adipose tissue mass
Regeneration of fat cells from myofibroblasts during wound healing
Circadian time signatures of fitness and disease
HDAC3-Dependent Epigenetic Pathway Controls Lung Alveolar Epithelial Cell Remodeling and Spreading via miR-17-92 and TGF-β Signaling Regulation
Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion
Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock
MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells
Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo
ATF4 licenses C/EBPβ activity in human mesenchymal stem cells primed for adipogenesis
PPARγ and the global map of adipogenesis and beyond
Nutrient-sensing nuclear receptors coordinate autophagy
Integrator Regulates Transcriptional Initiation and Pause Release following Activation
Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions
The orphan nuclear receptors at their 25-year reunion
Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration
Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy