Area of research
Pulmonary and Respiratory Medicine · Oncology
Research interest
Research interests include Cancer research, Cell biology, Biology, Extracellular matrix, KRAS, and Wnt signaling pathway.
Human-correlated genetic models identify precision therapy for liver cancer
CXCR2 inhibition enables NASH-HCC immunotherapy
Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features
Author Correction: Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
CXCR2 inhibition enables NASH-HCC immunotherapy
NOTUM from Apc-mutant cells biases clonal competition to initiate cancer
A RAC-GEF network critical for early intestinal tumourigenesis
PYCR1-dependent proline synthesis in cancer-associated fibroblasts is required for the deposition of pro-tumorigenic extracellular matrix
TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence
Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function
TGFβ pathway limits dedifferentiation following WNT and MAPK pathway activation to suppress intestinal tumourigenesis