Area of research
Cell Biology · Pathology and Forensic Medicine
Research interest
Research interests include Proteoglycans and glycosaminoglycans research, Spine and Intervertebral Disc Pathology, Osteoarthritis Treatment and Mechanisms, and Connective tissue disorders research.
Structure and Function of Ocular Proteoglycans: Essential Proteins for Vision.
COMP Is a Biomarker of Cartilage Destruction, Extracellular Matrix and Vascular Remodeling and Tissue Repair.
Glycosaminoglycans, Instructive Biomolecules That Regulate Cellular Activity and Synaptic Neuronal Control of Specific Tissue Functional Properties.
The biodiversity of KS-proteoglycans in cellular regulation and tissue function: emerging bioregulatory roles for low sulfation proteoglycans and bioconjugates.
The Potential of Bioactive Plant Phytochemicals, Pro-Resolving Anti-Inflammatory Lipids, and Statins in the Inhibition of Intervertebral Disc Degeneration, Low Back Pain Resolution, Disc Functional Repair, and Promotion of Intervertebral Disc Regeneration.
Intervertebral Disc Proteoglycans: Multifunctional Tissue Stabilizing and Instructional Cell Regulatory Proteins That Control Tissue Homeostasis.
Keratan Sulfate Is a Multifunctional Brain Glycosaminoglycan With Instructive Capabilities.
The Impact of the Ovine Annular Lesion Model on IVD Pathobiology and Utility of the Ovine Spinal Model in Patho-Anatomical Studies: A Historical Perspective.
A Conceptual Review of Naturally Occurring Toxins and Venoms as Peptide Blockers to Combat Chronic Low Back Pain.
The Roles of Bacteria in the Microbiome–Intervertebral Disc Axis
CNS/PNS proteoglycans functionalize neuronal and astrocyte niche microenvironments optimizing cellular activity by preserving membrane polarization dynamics, ionic microenvironments, ion fluxes, neuronal activation, and network neurotransductive capacity.
Hippo cell signaling and HS-proteoglycans regulate tissue form and function, age-dependent maturation, extracellular matrix remodeling, and repair.
Diverse and multifunctional roles for perlecan (<i>HSPG2</i>) in repair of the intervertebral disc.
Lumican, a Multifunctional Cell Instructive Biomarker Proteoglycan Has Novel Roles as a Marker of the Hypercoagulative State of Long Covid Disease.
Biomimetic Proteoglycans for Intervertebral Disc (IVD) Regeneration.
Dystroglycan-HSPG interactions provide synaptic plasticity and specificity.
Keratan sulfate, an electrosensory neurosentient bioresponsive cell instructive glycosaminoglycan.
Impaired instructive and protective barrier functions of the endothelial cell glycocalyx pericellular matrix is impacted in COVID-19 disease.
Amyloid, a Jekyll and Hyde Molecule Inducing Neuronal Decline and Cognitive Dysfunction is Also a Unique Molecular Template used in Nano-electronics, Light Capture Photovoltaics, and Biosensors in Neuromorphic Computing.
Intervertebral disc degeneration and how it leads to low back pain.
The Potential of Flavonoids and Flavonoid Metabolites in the Treatment of Neurodegenerative Pathology in Disorders of Cognitive Decline
An update on animal models of intervertebral disc degeneration and low back pain: Exploring the potential of artificial intelligence to improve research analysis and development of prospective therapeutics
The Potential of Flavonoids and Flavonoid Metabolites in the Treatment of Neurodegenerative Pathology in Disorders of Cognitive Decline.
An update on animal models of intervertebral disc degeneration and low back pain: Exploring the potential of artificial intelligence to improve research analysis and development of prospective therapeutics.
The Glycosaminoglycan Side Chains and Modular Core Proteins of Heparan Sulphate Proteoglycans and the Varied Ways They Provide Tissue Protection by Regulating Physiological Processes and Cellular Behaviour
The Glycosaminoglycan Side Chains and Modular Core Proteins of Heparan Sulphate Proteoglycans and the Varied Ways They Provide Tissue Protection by Regulating Physiological Processes and Cellular Behaviour.
HS, an Ancient Molecular Recognition and Information Storage Glycosaminoglycan, Equips HS-Proteoglycans with Diverse Matrix and Cell-Interactive Properties Operative in Tissue Development and Tissue Function in Health and Disease.
Hyaluronan hydrates and compartmentalises the <scp>CNS</scp>/<scp>PNS</scp> extracellular matrix and provides niche environments conducive to the optimisation of neuronal activity
Hyaluronan hydrates and compartmentalises the CNS/PNS extracellular matrix and provides niche environments conducive to the optimisation of neuronal activity.
Pentosan Polysulfate Affords Pleotropic Protection to Multiple Cells and Tissues.