Area of research
Immunology · Pathology and Forensic Medicine
Research interest
Research interests include Lymphoma Diagnosis and Treatment, Immune Cell Function and Interaction, Hematopoietic Stem Cell Transplantation, and Receptor Mechanisms and Signaling.
A µ-opioid receptor superagonist analgesic with minimal adverse effects
A randomized phase 2 study of ipilimumab, nivolumab, and brentuximab vedotin in patients with relapsed Hodgkin lymphoma
A µ-opioid receptor superagonist analgesic with minimal adverse effects.
Snapshots of the dynamic basis of NTSR1 G protein subtype promiscuity.
Author Correction: A µ-opioid receptor superagonist analgesic with minimal adverse effects.
MIC: A deep learning tool for assigning ions and waters in cryo-EM and crystal structures
Non-Equilibrium Snapshots of Ligand Efficacy at the μ-Opioid Receptor
MIC: A deep learning tool for assigning ions and waters in cryo-EM and crystal structures.
Therapy duration and improvement of ventricular function in <i>de novo</i> heart failure: the Heart Failure Optimization study
Allosteric modulation and G-protein selectivity of the Ca<sup>2+</sup>-sensing receptor.
Metric Ion Classification (MIC): A deep learning tool for assigning ions and waters in cryo-EM and x-ray crystallography structures
A Putative Binding Model of Nitazene Derivatives at the
<i>μ</i>
-Opioid Receptor
Insights into distinct signaling profiles of the µOR activated by diverse agonists.
Structure-based design of bitopic ligands for the µ-opioid receptor.
Structural basis for activation of CB1 by an endocannabinoid analog.
Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity
Bespoke library docking for 5-HT<sub>2A</sub> receptor agonists with antidepressant activity.
Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD
The tethered peptide activation mechanism of adhesion GPCRs.
Structure determination of inactive-state GPCRs with a universal nanobody.
Structure and mechanism of the SGLT family of glucose transporters.
Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns.
The oxytocin signaling complex reveals a molecular switch for cation dependence.
Plasticity in ligand recognition at somatostatin receptors.
Development of OPLS-AA/M Parameters for Simulations of G Protein-Coupled Receptors and Other Membrane Proteins.
Author Correction: Plasticity in ligand recognition at somatostatin receptors.
Structure and mechanism of the SGLT family of glucose transporters
G-protein activation by a metabotropic glutamate receptor.
Asymmetric activation of the calcium-sensing receptor homodimer.
Isolating Conformers to Assess Dynamics of Peptidic Catalysts Using Computationally Designed Macrocyclic Peptides.